2010 Protein Folding Dynamics Gordon Research Conference and Seminar in Ventura, CA from January 9-15, 2010

第五届戈登蛋白质折叠动力学研究会议和研究生研究研讨会将于2010年1月9日至10日（GRS）和1月10日至15日（GRC）在加利福尼亚州文图拉的文图拉海滩万豪酒店举行，这是一个针对蛋白质折叠方法和模型的研究生和博士后的研讨会。国家科学基金会的资助将允许在该领域工作的年轻和成熟的科学家广泛参与。蛋白质折叠是解决生物学基本问题的多学科研究领域。因此，很少有其他领域看到如此成功的物理和生物科学的结合。渐渐地，越来越多的实验和理论结合的研究正在发表，这种结合正在推进我们对蛋白质序列中编码信息的基本定量理解。技术和理论的进步已经改变了我们对蛋白质折叠和动力学的看法。快速事件可以在接近全原子分子动力学模拟的时间尺度上通过实验观察到。新的、复杂的蛋白质模型允许对集合动力学进行采样并与实验进行比较。戈登蛋白质折叠动力学研究会议是一个相对较新的会议，于2002年首次成立，旨在将实验和理论结合起来，探索该领域的进展，并作为一个论坛，讨论多肽能量学和动力学的基本问题；目的：探讨蛋白伴蛋白辅助折叠及其与疾病的关系。更广泛的影响：随着该领域的成熟和物理科学的发展被应用于蛋白质动力学和能量学的重要问题，提供这个场所来促进理论和实验之间的交流和培训变得更加重要。GRC营造了一个环境，吸引了社区中最聪明、最具互动性的成员。在本次会议上提出的想法和假设将继续推动蛋白质折叠动力学领域的发展，以及对理解蛋白质序列编码信息感兴趣的更大的社区，从生物材料到人类遗传学等各个领域。蛋白质折叠动力学研究生研究研讨会是作为蛋白质折叠动力学GRC的卫星会议组织的会议。本次研讨会为研究生和博士后科学家提供了一个场所，i)为蛋白质折叠动力学中的GRC准备当前技术，理论和模型的背景，ii)分享他们对蛋白质折叠方法和技术的知识，iii)见面并讨论他们自己的研究。年轻和发展中的科学家的参与代表了会议愿景中的一个关键目标，即为这个充满活力的多学科研究领域提供广泛基于实验蛋白质折叠方法和模型和理论的科学家，这些模型和理论为该领域的实验解释提供了基础。

The 5th Gordon Research Conference on Protein Folding Dynamics and the accompanying Graduate Research Seminar, which is a workshop for graduate students and post docs addressing the methods and models of protein folding will take place at the Ventura Beach Marriott,Ventura, California from January 9-10 (GRS) and January 10-15 (GRC), 2010. Funding from the NSF will allow a broad participation from both young and established scientists working in this field. Protein folding is a multidisciplinary area of research addressing fundamental problems in biology. Consequently, few other fields see such a successful blend of physical and biological sciences. Progressively, more studies that bring together experiment and theory are being published, and this combination is advancing our fundamental quantitative understanding of the information encoded within protein sequences. Technological and theoretical advances have altered our view of the protein folding and dynamics. Fast events can be observed experimentally on timescales that approach those accessible by all-atom molecular dynamics simulations. New,sophisticated models of proteins allow ensemble kinetics to be sampled and compared to experiment.The Gordon Research Conference in Protein Folding Dynamics, is a relatively new conference,first set up in 2002, aimed specifically to bring experiment and theory together to explore advances in the field and to serve as a forum to discuss fundamental problems from polypeptide energetics and dynamics; to chaperone assisted folding and the relationship between protein misfolding and disease.Broader Impacts: As the field matures and development in the physical sciences are being applied to important problems in protein dynamics and energetics, it becomes even more important to provide this venue to foster this communication and training at this interface between theory and experiment. The GRC fosters an environment that attracts the brightest and the most interactive members of the community. The ideas and hypotheses developed at this conference will continue to advance the field of protein folding dynamics as well as larger community interested in understanding the information encoded in protein sequences, fields as diverse as biomaterials to human genetics.The Graduate Research Seminar in Protein Folding Dynamics is a meeting being organized as a satellite to the GRC in Protein Folding Dynamics. This workshop serves as a venue for graduate students and postdoctoral scientists to i) develop background on current techniques, theories and models in preparation for the GRC in Protein Folding Dynamics, ii) share their knowledge of protein folding methodologies and techniques and iii) meet each other and discuss their own research. The involvement and inclusion of young and developing scientists represents a key objective in the vision of the conference to provide this vibrant multi-disciplinary research area with scientists who are broadly based in both experimental protein folding methodologies and the models and theories that provide a basis for the interpretation of experiment in this field.