RCN-UBE: Microbial Genome Annotation Network

该奖项将支持由社区学院、本科院校和研究型大学的教育工作者组成的网络，与能源部联合基因组研究所（DOE-JGI）一起，为本科生提供可获取、廉价和真实的基因组注释研究经验。基因组注释是将生物信息附加到DNA序列数据上的过程。虽然这个过程的某些部分可以用基于计算机的算法来完成，但这些分析的评估和功能遗传分析最好由研究人员来完成。这些步骤为学生提供了学习和应用当前研究工具的机会，并为大型研究工作做出贡献。微生物基因组序列数据和使用在线注释工具的培训将由DOE-JGI提供。该网络将招募、培训和指导新成员，并开发新的课程，鼓励从初级到高级生物学课程的真实研究经验。该项目的智力价值将包括通过相关研究的主动和基于探究的学习策略加强学生在生物科学方面的学习，增加生物科学学生的保留率，包括来自代表性不足的群体的学生，以及在快速发展的基因组注释领域的教师发展。该项目更广泛的影响将包括创建一个庞大而多样化的教育工作者和学生群体，参与推动微生物基因组科学领域的真正研究，促进网络成员和其他感兴趣的研究人员之间的互动，关注一个有长期潜力的科学问题，作为一个充满活力的研究项目；创建一个全国性的模式，将基于注解的研究纳入本科课程，并为许多学生提供参与真实研究的机会，特别是在社区大学，这些学生通常无法承担广泛和综合研究经验的时间和费用。该项目由生物科学局和本科教育司联合支持。

This award will support a network of educators from community colleges, undergraduate institutions, and research universities, together with the Department of Energy-Joint Genome Institute (DOE-JGI), that will provide accessible, inexpensive, and authentic research experience in genome annotation to undergraduate students. Genome annotation is a process that attaches biological information to DNA sequence data. Although some parts of this process can be performed with computer-based algorithms, evaluation of those analysis and functional genetic analysis are best performed by researchers. Those steps provide the opportunity for students to learn and apply current research tools and contribute to a large research effort. Microbial genome sequence data and training in the use of online annotation tools will be provided by the DOE-JGI. The network will recruit, train and mentor new members, and develop new curricula that encourage authentic research experiences in entry-level through advanced biology courses. The intellectual merits of the project will include enhanced student learning in the biological sciences through the active and inquiry-based learning strategy of relevant research, increased retention of students in the biological sciences, including students from underrepresented groups, and faculty development in the rapidly advancing field of genome annotation. The broader impacts of the project will include creation of a large and diverse cohort of educators and students participating in authentic research that advances the field of microbial genome science, fostering of interactions among the network's members and other interested researchers on a focused scientific question that has long-term potential as a vibrant research program; creation of a national model for incorporating annotation-based research into the undergraduate curriculum, and providing opportunities for many students to participate in authentic research, especially at community colleges that normally cannot afford the time and expense of an extensive and integrated research experience.This project is supported jointly by the Biological Sciences Directorate and the Division of Undergraduate Education.