MRI-R2: 120 kV Electron Microscope System for Sample Preparation, Biological Microscopy, Tomography, and Visualization of Protein Complexes

该奖项由2009年《美国复苏与再投资法案》(公法111-5)资助。这一重大研究仪器--复苏与再投资(MRI-R2)奖项为阿肯色大学医学院校园(UAMS)购置120千伏电子显微镜系统和辅助样品制备设备提供资金。该设备是为UAMS生理学和生物物理学、生物化学和分子生物学以及神经生物学和发育科学系的一群基础科学家的需求量身定做的。其他地区机构的研究人员也可以接触到新的显微镜。此次收购是朝着在阿肯色州建立唯一这样的生物电子显微镜设施迈出的重要一步。利用新系统的研究包括了解病毒学要素、高尔基体功能、神经生理学、内分泌分泌等更多主题。本科生和研究生都将从获得这种仪器中受益，因为研究人员正在从事博士生的研究培训，每年夏天都有大量本科生参加合作实验室的工作。新仪器支持的研究结果将在同行评议的期刊上传播，并通过学生和教职员工在区域和国家会议上的陈述进行传播。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This Major Research Instrumentation-Recovery and Reinvestment (MRI-R2) award funds the acquisition of a 120 kV electron microscopy system and supporting sample preparation equipment at the University of Arkansas Medical Sciences Campus(UAMS). The equipment is tailored to the needs of a group of basic scientists in the Departments of Physiology and Biophysics, Biochemistry and Molecular Biology, and Neurobiology and Developmental Sciences at UAMS. The new microscope is also accessible to investigators at other regional institutions. This acquisition is a major step toward establishing the only such biological electron microscope facility in the state of Arkansas. Research utilizing the new system includes studies to understand elements of virology, golgi apparatus function, neuronal physiology, endocrine secretion, and many more topics. Both undergraduate and graduate students will benefit from the acquisition of this instrumentation as investigators are engaged in the training of Ph.D. students in research, and each summer there is significant participation of undergraduates in the collaborating laboratories. Results from the studies enabled by the new instrumentation will be disseminated in peer-reviewed journals, and through students and faculty presentations at regional and national meetings.