Collaborative Research: Genomics as the Foundation of a New Undergraduate Curriculum

生物科学(61)亚利桑那州立大学与梅萨社区学院和西雅图太平洋大学合作，正在实施以基因组学为重点、以研究为基础的方法来教授核心生物科学课程。这个项目的智力价值在于，所涉及的课程通过将所有课程整合到一个涉及多个学校和教育水平的高度协作的大型基因组研究项目中，教授关键概念和技能。该计划是跨学科的，由课程组成，在这些课程中，细菌基因组项目是在几个学期的课程中启动、完成和发表的。课程工作本身就是一个研究项目，学生学习所有必要的技能和概念，因为项目的每个新阶段都需要更高水平的专业知识。许多学生还发起个人研究项目来跟进他们的课堂工作。这种教学方法是由皮斯莱特和他的合作者古德纳博士开发的，当时他们对农杆菌基因组进行了测序(古德纳等人，科学。294：2323，后者有十几个本科生作为合著者)，此后由古德纳博士和他在希拉姆学院的同事们非常成功地实施(古德纳等人，ASM新闻)。69：584)。该方法包括整合实验室机器人部分，并扩展与梅萨社区学院的持续合作。这一提议的更广泛影响包括改善大学与当地社区学院区之间的努力衔接，改善STEM领域的学生招生和留住，重点努力招募少数族裔，本科生对科学文献做出重大贡献，以及拥有丰富的智力、技术和沟通技能的毕业生。正在制作详细的材料，并将其传达给其他机构的教育工作者。

Biological Sciences (61)Arizona State University in collaboration with Mesa Community College and Seattle Pacific University is implementing a genomics-focused, research-based approach for teaching the core biological science classes. The intellectual merit of this project is that the courses involved teach critical concepts and skills by integrating all courses into a large, highly collaborative genomics research project that involves multiple schools and educational levels. The program is interdisciplinary, consisting of courses in which bacterial genome projects are initiated, completed, and published over the course of several semesters. The course work is itself a research project, and the students learn all of the necessary skills and concepts as each new stage of the project requires a new level of expertise. Many students also initiate individual research projects to follow-up their classroom work. This method of teaching was developed by PI Slater and his collaborator Dr. Goodner when they sequenced the Agrobacterium tumefaciens genome (Goodner et al.,Science. 294:2323, the latter publication had over a dozen undergraduates as coauthors) and has since been very successfully implemented by Dr. Goodner and his colleagues at Hiram College (Goodner et al., ASM News. 69:584). The approach includes integration of a laboratory robotics component and extends an ongoing collaboration with Mesa Community College.The broader impacts of this proposal include improved articulation of efforts between the university and a local community college district, improved recruitment and retention of students in STEM fields, a focused effort on minority recruitment, significant contributions by undergraduate students to the scientific literature, and graduates with a rich set of intellectual, technical and communications skills. Detailed materials are being produced and communicated to educators from other institutions.