REU Site: Research Experience for Undergraduates in Chemistry and Biochemistry

该奖项由数学和物理科学局的化学部(CHE)和生物科学局的生物基础设施部(DBI)颁发，以支持由加州州立大学洛杉矶分校Scott Nickolaisen领导的本科生研究体验(REU)网站。该网站支持的研究项目涉及多个化学领域，但也有一些属于生物-化学领域的研究项目。本科生将主要从缺乏支持本科生研究的基础设施的机构招募，包括来自代表性不足群体的学生，特别是洛杉矶盆地的社区大学学生。该网站将在为期十周的计划中，每年夏天为十名学生提供支持。本科生将从事的项目样本包括：(1)开发和应用磁共振技术来研究与生物相关的大分子的物理化学性质；(2)研究环境污染物在凝聚相中的光化学反应；(3)研究饮食因素如何调节高密度脂蛋白的代谢；(4)研究磷酸烯醇式丙酮酸羧基酶的变构激活部位；(5)制备具有新的工程特征的非球对称树枝状大分子，如峡谷、裂隙和口袋；(6)较大(两个以上的碳)烷基过氧基与其他大气组分的反应动力学研究。除了在暑期进行研究外，参加这个项目的学生还将参加一些专业发展活动，包括负责任的研究行为、实验室安全和科学交流方面的培训。作为培训的一部分，年轻科学家需要接触到现代研究方法和工具。这个REU网站旨在为没有重大研究经验的学生提供机会，在这个以本科生为主的机构中，在敬业的教师指导下进行化学科学的尖端研究。在这个地点参与研究的不同学生群体将为进一步学习化学科学、研究生院以及最终成为该国技术劳动力的一部分做好充分准备。

This award from the Division of Chemistry (CHE) in the Mathematical and Physical Sciences Directorate and the Division of Biological Infrastructure (DBI) in the Biological Sciences Directorate supports a Research Experience for Undergraduates (REU) site led by Scott Nickolaisen at California State University - Los Angeles. The research projects supported in this site are in a number of areas of chemistry, but with a number of projects at the Biology-Chemistry interface. Undergraduates will be recruited to this site primarily from institutions that lack infrastructure to support undergraduate research, including students from underrepresented groups, with a particular emphasis on community college students in the Los Angeles basin. The site will support ten students per summer in a ten week program. A sample of the projects that undergraduates will work on include: (1) the development and application of magnetic resonance techniques for the study of the physicochemical properties of biologically related macromolecule; (2) the study of the photochemical reactions of environmental pollutants in condensed phases; (3) the study of how dietary factors regulate the metabolism of high density lipoproteins; (4) the study of the allosteric activation sites of the enzyme phosphoenolpyruvate carboxylase; (5) the preparation of non-spherically symmetric dendrimers with novel, engineered features such as canyons, clefts, and pockets and (6) the study of the reaction kinetics of larger (more than two carbons) alkyl peroxy radicals with other atmospheric constituents. In addition to conducting research during the summer, the students participating in this program will participate in a number of professional development activities, including training on the responsible conduct of research, laboratory safety, and scientific communication.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide students without significant research experience a chance to conduct cutting-edge research in the chemical sciences with dedicated faculty mentors at this predominantly undergraduate institution. The diverse student cohort participating in research at this site will be well-prepared for further study in the chemical sciences, graduate school, and eventual employment as part of the country's technical workforce.