Center for Pharmaceutical Development

0968003格鲁吉亚理工学院; Andy Bommarius 0968972堪萨斯大学; Eric Munson本提案的目的是启动一个新的I/UCRC“药品生产和制剂”（CPMF），重点是解决制药行业当前的挑战，并开发解决方案，以实现更具选择性和稳健的生产工艺、更稳定的制剂以及更好的特征和一致的产品。拟议中心的牵头机构是格鲁吉亚理工学院，其选址在堪萨斯大学。CPMF建议探索对药品生产和改进药品配方重要的领域。该中心计划开发方法和技术，以生产更好的药物，使其持续时间更长，更有效，更安全。通过结合格鲁吉亚理工学院、迪克讷大学和堪萨斯大学的努力，PI提出了一些潜在的重要项目，这些项目可以大大提高制造更好药品所需的应用知识。CPMF将允许制药公司以较低的成本以合作方式推进风险研究，从而可以在分担风险和互利的情况下追求重要的制造需求和创新。CPMF已经组建了一个非常强大的研究小组，他们非常有资格进行提案中概述的研究。该中心将促进安全有效药物和药物制剂的快速开发，并将确定拟议药物制剂的潜在问题，具有改善甚至挽救人类生命的潜力。该中心计划让研究生和博士后同事参与执行和展示他们的研究，从而为他们创造一个与制药和医疗领域同行互动的机会。传播成果的计划是经过深思熟虑的，受众也是适当的。拟议中的中心还计划把重点放在招募代表性不足的群体。

0968003 Georgia Tech; Andy Bommarius 0968972 University of Kansas; Eric Munson The purpose of this proposal is to start a new I/UCRC "Pharmaceutical Manufacturing and Formulation" (CPMF) with a focus on addressing current challenges in the pharmaceutical industry, and developing solutions towards more selective and robust manufacturing processes, more stable formulations, and better characterized and consistent products. The lead institution of the proposed Center is Georgia Tech with a site location at the University of Kansas. CPMF proposes to explore areas important to pharmaceutical manufacturing and improved formulations for pharmaceuticals. The Center plans to develop methods and technologies that will produce better pharmaceuticals, make them last longer, be more effective, and safer. By combining the efforts of Georgia Tech, Duquesne University and the University of Kansas, the PIs have proposed a number of potentially important projects that could significantly advance the applied knowledge necessary to make better pharmaceuticals. CPMF will allow pharmaceutical companies a lower cost approach to advancing risky research in a cooperative manner such that important manufacturing needs and innovations can be pursued with shared risk and mutual gain. CPMF has assembled a very strong group of researchers who are well-qualified to perform the research outlined in the proposal. The proposed Center will promote the rapid development of safe and efficacious drugs and drug formulations, and will identify potential problems with proposed drug formulations, with the potential of improving or even saving human lives. The Center plans to involve graduate students and post-doctoral associates in performing and presenting their research, thereby creating an opportunity for them to interact with counterparts from pharmaceutical and medical areas. Plans for dissemination of results are well thought out and audiences are appropriate. The proposed Center also plans to put emphasis on recruiting under-represented groups.