MRI: Acquisition of Computational Resources for Research in Computational and Systems Biology

提案编号：12- 29064 PI：Camacho，卡洛斯J; Chong，Lillian T机构：爱丁堡大学标题：MRI/采集：计算和系统生物学研究的计算资源项目建议：该项目，获得计算仪器，促进跨学科合作和培训，促进生物科学的突破。该项目由计算与系统生物学系（DCSB）与联合博士学位共同领导。匹兹堡大学和卡内基梅隆大学是该地区两所大学之间的合作项目。此次收购是一个最先进的57节点3392核心计算集群，致力于应用程序的研究和开发以及新计算方法的传播。该集群支持以下研究项目：-新的分子方法来访问感兴趣的生物时标; -深度测序技术的高通量？omic？数据收集;- 在基础研究中利用高分辨率多模态生物医学图像/视频的方法。更广泛的影响：区域和国家都应感受到更广泛的影响。在有关机构，研究倡议将开发的应用程序纳入教学模块，供当地城市高中以及本科和研究生课程使用。访问专用的计算资源将为学生提供宝贵的实践经验。更广泛地说，开发的软件利用了新的计算资源，将提供给全国其他研究人员。

Proposal #: 12-29064PI(s): Camacho, Carlos J; Chong, Lillian TInstitution: University of PittsburghTitle: MRI/Acq.: Computational Resources for Research in Computational and Systems BiologyProject Proposed:This project, acquiring a computational instrument, fosters interdisciplinary collaborations and training that promote breakthroughs in the biological sciences. The project is lead by the Department of Computational and Systems Biology (DCSB) in conjunction with the joint Ph.D. program between two institutions in the area: Pittsburgh and Carnegie Mellon Universities. The acquisition, a state-of-the-art 57-node 3392 core computing cluster, is dedicated to research and development of applications and the dissemination of new computational methods. The cluster supports the following research projects:- Novel molecular methods to access biological timescales of interest; - Deep-sequencing technologies for high throughput ?omic? data collection; and, - Methods to leverage high-resolution multi-modal biomedical images/videos in basic research.Broader Impacts: Broader impacts should be felt both regionally and nationally. At the involved institutions, the research initiatives the incorporation of developed applications in teaching modules for use at local city high schools, as well as in undergraduate and graduate courses. Access to dedicated computational resources will provide valuable hands on experiences for students. More broadly, the software developed exploits the new computational resources that will be made available to other researchers nationwide.