EAGER: A New Analyzer for In-Situ Characterization of Engineered Nanoparticles

摘要#1230189 Sadik，Omowunmi A.智能价值需要新颖的环境纳米颗粒分析仪和方法来评估工程纳米材料带来的风险。解决围绕负责任地发展纳米技术的复杂和关键问题，对社会和环境都很重要。随着技术的进步，社会的进步往往导致同时出现对人类健康、生态系统或对两者的不利影响。新兴的环境纳米技术领域是一个关键的研究领域，如果得到迅速而迫切的支持，这一领域将大大受益。因此，这项研究的直接目标是开发一种与环境相关的便携式纳米粒子分析仪，它可以直接从纯标准、模拟基质和真实世界样品中测量不同水平的纳米材料。这项拟议的研究有望弥合与纳米材料潜在的环境健康和安全(EH和S)问题相关的知识和方法空白。由此产生的技术应该提供关于纳米颗粒的大小或形状的信息，这是确定毒性的重要因素；并将它们与自然存在的颗粒区分开来。研究将利用一种新型的柔性、光学透明的导电纳米孔膜来同时捕获、分离和检测工程纳米材料。选定的金属氧化物和碳基纳米材料将通过集成电化学、聚酰胺酸膜和切向流过滤进行测试，以创建一个可在现场使用的系统。广泛影响该项目的一个主要成果是一个与环境相关的便携式传感器系统，它可以直接从环境样本中测量各种纳米材料的水平，并可能通过过滤来补救它们。该方法提供了有关纳米材料的尺寸和其他物理参数的信息，这对确定纳米材料的毒性很重要。这种方法可以为环境和安全应用带来巨大的好处，因为便携式分析仪可以部署在许多地方，以保护环境、公共安全和安保。这项研究将为研究生提供良好的培训经验，并为本科少数民族学生提供接触野外环境分析的机会。此外，这项研究将支持加强现有的研究生和本科课程，包括化学与环境(CHEM 552C/482C)和传感器与生物电子学(CHEM 424/524)。其他传播计划包括在国家会议上作介绍以及在相关领域的同行评议期刊上发表联合出版物。

Abstract#1230189Sadik, Omowunmi A.Intellectual MeritNovel environmental nanoparticle analyzers and methods are needed to assess the risks posed by engineered nanomaterials. Addressing the complex and critical issues surrounding the responsible development of nanotechnology is important both for society and the environment. The progress of society as technological advances are introduced has often resulted in the simultaneous emergence of adverse effects either for human health, the ecosystem or both. The emerging field of environmental nanotechnology is a critical research area, and one which would greatly benefit from a rapid EAGER support. Hence, the immediate goal of this research is to develop an environmentally-relevant, portable nanoparticle analyzer which can measure various levels of nanomaterials directly from pure standards, simulated matrices and real-world samples. The proposed research is expected to bridge the knowledge and methodology gaps associated with the potential environmental health and safety (EH&S) issues of nanomaterials. The resulting technology should provide information about the size or shape of the nanoparticle, which are important factors for determining toxicity; as well as distinguish them from naturally-occurring particles.The research will make use of a new class of flexible, optically transparent conducting nanoporous membranes to simultaneously capture, isolate and detect engineered nanomaterials. Selected metal oxides and carbon based nanomaterials will be tested by integrating electrochemistry, polyamic acid membranes and tangential flow filtration to create a system that can be used in situ.Broader ImpactsA major outcome of this project is an environmentally-relevant portable sensor system which can measure the levels of various nanomaterials directly from the environmental samples and possibly remedy them via filtration. The approach provides information regarding the size and other physical parameters of the nanomaterials, which are important in determining nanomaterials toxicity. This approach can be of great benefit for environmental and security applications because the portable analyzers can be deployed in many places to safeguard the environment, public safety, and security. This research will provide excellent training experience for graduate students as well as train undergraduate minority students who will gain exposure to field environmental analysis. Further, this research will support the enhancement of existing graduate and undergraduate courses including Chemistry and the Environment (CHEM 552C/482C) and Sensors and Bioelectronics (CHEM 424/524). Other dissemination plans include presentations at national conferences and joint publications in peer-reviewed journals in related fields.