How motor action shapes emotion in the brain

_____________________________________________________________________________ 人类经验的多样性是如何反映在大脑/介意吗?什么是大脑和精神的普遍性，什么取决于人们的身体和社会经历的细节？这个项目探讨了我们的身体行为是如何影响情绪的神经处理的。该研究的问题是，左撇子和右撇子的许多行为方式不同，他们是否使用相应不同的大脑区域来处理人类情感的最基本组成部分之一：情感动机（我们倾向于接近或避免物理或社会刺激）。由芝加哥大学的Daniel Casasanto博士领导的研究小组将使用行为任务、脑成像和神经刺激相结合的方法来验证一个假设，即人们用手进行与接近相关的动作和与回避相关的动作的方式可能决定了与接近和回避相关的情绪如何在大脑中表现出来。本基础研究具有重要的临床意义。fda批准的神经疗法目前用于治疗抑郁症和焦虑症。这些治疗方法是基于大脑和精神的一刀切模型。如果我们使用手的方式会影响情绪在大脑半球的分布，这可能表明对右撇子有益的治疗可能对左撇子有害。根据患者与世界互动的具体情况定制神经疗法，对于开发安全、有效的治疗常见心理健康问题的方法可能至关重要。

_____________________________________________________________________________How is the diversity of the human experience reflected in the brain/mind? What is universal about the brain and mind, and what depends on the particulars of people's physical and social experiences? This project explores how the actions we perform with our bodies shape the neural processing of emotion. It asks whether right- and left-handers, who perform many actions differently, use correspondingly different areas of the brain to process one of the most basic components of human emotion: affective motivation (our predisposition to approach or avoid physical or social stimuli). The research team, led by Dr. Daniel Casasanto at the University of Chicago, will use a combination of behavioral tasks, brain imaging, and neural stimulation to test the hypothesis that the way people use their hands to perform approach-related actions and avoidance-related actions may determine how approach- and avoidance-related emotions are represented in the brain. There are important clinical implications of this basic research. FDA-approved neural therapies are currently in use to treat depression and anxiety disorders. These treatments are based on a one-size-fits-all model of the brain and mind. If the way we use our hands influences how emotions are distributed across the cerebral hemispheres, this may signal that treatments that are beneficial for right-handers may be detrimental for left-handers. Tailoring neural therapies to the specifics of patients' interactions with the world may be crucial for developing safe, effective treatments for common mental health issues.