Carbon Nanotubes as an Intracellular Neural Electrode

这个项目的主要目标是开发一种纳米级的电生理探针，能够记录完整大脑中单个神经元内部和周围的电活动。探针将由单个碳纳米管（CNT）或由多个碳纳米管组成的小束组成，这些碳纳米管由磨尖的钨电极生长而成。该装置将被涂上一层聚对二甲苯，它将提供电绝缘，并为钨丝和碳纳米管之间的接触提供结构支撑。这个探针将是迄今为止最小的被动神经记录电极，为许多以前不可能的实验和医学应用打开了大门。公众文摘：该提案将使用纳米技术开发更敏感的电极，用于监测大脑中神经细胞的活动。这项新技术将提供有关神经系统疾病的更好信息，并可能导致更好地治疗这类疾病。

1265085 - DeWeeseThe primary goal of this project is to develop a nanometer-scale electrophysiological probe capable of recording the electrical activity both in and around individual neurons in the intact brain. The probe will consist of a single carbon nanotube (CNT) or a small bundle of multiple CNTs, grown from a sharpened tungsten electrode. The device will be coated with Parylene, which will provide electrical insulation as well as structural support for the contact between the tungsten wire and the CNT. This probe will be the smallest passive neural recording electrode ever built, by far, opening doors to many previously impossible experiments and medicalapplications.Public abstractThis proposal will use nanotechnology to develop more sensitive electrodes for monitoring activity of nerve cells in the brain. This new technology will provide better information about neurological diseases and may lead to better treatment of such diseases.