SusChEM: Polymer-Supported Frustrated Lewis Pair (FLP) Catalysis

在这项由化学系大分子、超分子和纳米化学计划资助的项目中，纽瓦克罗格斯大学的Frieder Jaekle将把受挫Lewis对(FLP)激活小分子的最新进展应用到聚合物支撑的催化中。将采取多管齐下的方法：(1)将寻求具有强Lewis酸(受体)和/或Lewis碱(给体)位(胺、膦、卡宾)的官能化的可溶性聚合物，这些位是空间受阻的，以允许形成“受挫的”Lewis对。(2)还将开发具有催化活性的Lewis酸和Lewis碱基的多孔聚合物的创新方法。我们将检验这些新材料在催化过程中的效果。除了开发可持续化学过程的社会益处外，该项目的更广泛影响包括在高度跨学科的研究环境中对本科生和研究生进行培训，让化学领域代表性较低的群体(例如，ACS项目种子高中学生、少数族裔本科生)参与进来，并通过聚合物和材料化学外联计划培养对化学可持续发展的认识。Jaekle教授还将于2014年在罗格斯-纽瓦克校园组织“美洲的硼”会议。拟议的工作通过开发用于加速化学反应的无金属催化剂来解决对新的可持续化学过程的需求。所提议的催化剂的成功制备预计将在许多使用催化的领域产生影响，例如精细化学合成、精炼和塑料制造。此外，这项研究可能带来新的可用工艺，减少对稀有和昂贵的金属、有毒副产品的依赖，以及产生的化学废物的数量。

In this project funded by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division, Frieder Jaekle of Rutgers University at Newark will apply recent advances in the activation of small molecules by frustrated Lewis pairs (FLPs) to polymer-supported catalysis. A multi-pronged approach will be taken: (1) soluble polymers will be pursued that are functionalized with strong Lewis acid (acceptor) and/or Lewis base (donor) sites (amines, phosphines, carbenes), which are sterically encumbered to allow for formation of "frustrated" Lewis pairs. (2) Innovative approaches to porous polymers that contain catalytically active Lewis acid and Lewis base groups will also be developed. The efficacy of these new materials in catalytic processes will be examined. In addition to the societal benefits of developing sustainable chemistry processes, the broader impacts of the project include the training of undergraduate and graduate students in a highly interdisciplinary research environment, involvement of students from groups underrepresented in chemistry (e.g. ACS Project SEED high school students, minority undergraduate students), and creating awareness of sustainability in chemistry through a Polymer and Materials Chemistry Outreach Program. The Professor Jaekle will also organize the "Boron in the Americas" meeting in 2014 at the Rutgers-Newark campus.The proposed work addresses the need for new sustainable chemistry processes by developing metal-free catalysts for accelerating chemical reactions. Successful preparation of the proposed catalysts is expected to have an impact in many areas that employ catalysis, such as fine chemical synthesis, refining, and plastics manufacturing. Additionally, this research could lead to new processes available that will reduce reliance on rare and costly metals, toxic byproducts, as well as the amounts of chemical waste generated.