2013 Biological Mechanisms in Evolution: Basic Biology, Cancer, Infectious Disease & Medicine, June 2 - 7, 2013 at Stonehill College in Easton, MA
2013 Biological Mechanisms in Evolution: Basic Biology, Cancer, Infectious Disease & Medicine, June 2 - 7, 2013 at Stonehill College in Easton, MA
批准号:
1338919
负责人:
Susan Rosenberg
金额:
$2.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-06-01 至 2013-11-30
中文摘要
戈登进化生物机制研究会议:在基础生物学,癌症,传染病和医学,2013年6月2-7日在斯通希尔学院,伊斯顿,MA将带来当前的生物机制的理解,包括基因组可塑性的分子机制,诱变,基于蛋白质和rna的遗传,表观遗传学,压力,应激反应,随机性,表型变异和可塑性,承担对进化的理解,以及许多由进化驱动的基础科学问题。进化生物学和机械分子遗传学、基因组学和分子生物学等领域将联合起来,重点研究后者对我们理解进化的贡献。20世纪初的现代合成,孕育了现代进化生物学,早于分子生物学革命。传统的进化生物学并不总是跟上基因遗传基本假设的变化和非基因遗传的发现,这些发现来自于分子机制的研究。同样,分子生物学常常忽略了进化在重要的基础生物学问题中的关键作用。这次会议的目的是为了使越来越多的研究人员试图将分子生物学机制应用于对进化的理解。目标是催化整合的,机械的观点,进化机制运作的机制和它们的后果在医学和基础生物学。虽然分子生物学只是最近才开始渗透到进化生物学的领域,但这些学科的整合对于更深入地理解进化和生物学是至关重要的。这次会议将为研究人员提供一个家和社区。GRC项目将邀请年轻和更成熟的研究人员进行口头和海报演讲,重点关注该领域最好的新兴科学。GRC将为参与者提供最先进的观点,即通过理解驱动进化的基本生物机制,我们对进化机制的理解发生了一场革命。GRC将促进物理学家和生物学家之间的国际和国家合作,旨在了解基本的分子和生物学机制,并将这种理解应用于疾病和基础生物学的进化。它还将为年轻科学家提供交流机会、灵感和联系、指导,并为处于职业生涯关键阶段的年轻参与者提供前沿新研究的视角。国家科学基金会的资金将用于支付研究生、博士后、新研究者、尤其是女性和少数族裔参与者的费用。
英文摘要
The Gordon Research Conference on Biological Mechanisms in Evolution: in Basic Biology, Cancer, Infectious Disease and Medicine, 2-7 June 2013 at Stonehill College, Easton, MA will bring current understanding of biological mechanisms, including molecular mechanisms of genome plasticity, mutagenesis, protein- and RNA-based inheritance, epigenetics, stress, stress responses, stochasticity, and phenotypic variation and plasticity, to bear on understanding of evolution, and many basic-science problems driven by evolution. The fields of evolutionary biology and mechanistic molecular genetics, genomics and molecular biology, focusing on the contributions of the latter to our understanding of evolution will be united. The modern synthesis of the early twentieth century, which gave birth to current evolutionary biology, predated the molecular biology revolution. Traditional evolutionary biology has not always kept pace with changes to the basic assumptions of genetic inheritance and discoveries of non-genetic inheritance that have come from studies on molecular mechanisms. Similarly, molecular biology has often ignored the critical roles of evolution in important basic-biological problems. This meeting is aimed at the growing body of investigators attempting to bring molecular biological mechanisms to bear on understanding of evolution. The goals are to catalyze integrated, mechanistic views of mechanisms of evolution operating today and their consequences in medicine and basic biology. Although molecular biology is only recently beginning to penetrate the arena of evolutionary biology, integration of these disciplines is crucial for deeper understanding of evolution and biology in general. This meeting will give a home and community to researchers doing this. The GRC program will include invited and contributed oral and poster presentations by both younger and more established researchers, focusing on the best emerging science in the field. The GRC will provide participants a state-of-the-art view of a revolution in our understanding of the mechanisms of evolution brought about by understanding the fundamental biological mechanisms that drive it. The GRC will promote international and national collaboration between physicists and biologists, aimed at understanding fundamental molecular and biological mechanisms, and bringing this understanding to bear on evolution in disease and basic biology. It will also provide networking opportunities, inspiration and connections for young scientists, mentoring, and perspectives on cutting-edge new research for younger participants at a critical stage in their careers. The NSF funds will be used to defray the costs of a diverse group of graduate students, postdocs, new investigators and women and minority participants particularly.
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