Molecular characterization of stem cell differentiation and oocyte maturation using synchrotron infrared spectroscopy and Atomic Force Microscopy/Raman imaging
Molecular characterization of stem cell differentiation and oocyte maturation using synchrotron infrared spectroscopy and Atomic Force Microscopy/Raman imaging
批准号:
DP0878464
负责人:
Prof Bayden Wood
金额:
$43.92万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2012-12-31
中文摘要
目前还没有基于分子的方法在单细胞水平上评估卵母细胞成熟和干细胞分化。因此,要使澳大利亚在这一迅速扩大的领域走在前列,对这种技术的需要至关重要。这项技术将使澳大利亚在干细胞和卵母细胞研究方面处于领先地位,并最终帮助发现治疗衰弱的神经退行性疾病和脊髓损伤的疾病疗法,而确定卵母细胞活力的技术可能对未来的体外受精项目具有重要意义。这项研究开发的知识产权和技术也可能对全球市场产生影响。
英文摘要
There are currently no molecular based methods to assess oocyte maturation and stem cell differentiation at the single cell level. Consequently the need for such techniques is critical in placing Australia at the forefront in this rapidly expanding field. Such technology would give Australia a leading edge in stem cell and oocyte research and ultimately assist in discovering disease cures for debilitating neurodegenerative diseases and spinal chord injury, while techniques for determining the viability of oocytes may have important implications for future in vitro fertilization programs. The intellectual property and technologies developed from this research could also have potential to impact on the global market.
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海外基金