CIF21 DIBBs: PD: Accelerating Comparative Metagenomics through an Ocean Cloud Commons

Tara海洋探险队为世界上任何科学项目提供了最大的基因组学公开可用的连续数据集。一个由多国科学家组成的研究小组利用塔拉号研究船和现代测序技术以及最先进的成像技术，在所有主要海洋区域的数百个地点和深度取样了微小的浮游生物。塔拉海洋考察队的数据已经公布，但对研究人员来说，获取、操纵和分析如此大规模的资源是一个挑战。该项目创建了一个海洋云共享（OCC），这是一个基于云的资源和存储库，允许研究人员在云中查询塔拉海洋探险数据；它还通过海洋宝盒（OTB）提供比较宏基因组工具。海洋云共享和海洋宝箱建立在与CyVerse网络基础设施、Agave平台、OpenCloud和德克萨斯高级计算中心的计算设施等组织建立的合作伙伴关系之上。Ocean Cloud Commons使用基于MapReduce的算法，在Hadoop大数据框架下创建比较宏基因组数据资源。OCC可以被研究人员使用在海洋宝盒中开发的工具广泛访问，并在CyVerse网络基础设施中作为应用程序实现。具体来说，OTB工具通过CyVerse的Agave平台和开发者API在OpenCloud中部署和计算OCC数据。总而言之，OTB工具和OCC数据资源使研究人员能够解决影响气候和生态系统功能的海洋微生物分布的全球尺度问题。该奖项由高级网络基础设施部颁发，由美国国家科学基金会生物科学理事会（生物基础设施部）和美国国家科学基金会地球科学理事会共同支持。

The Tara Oceans Expedition has provided the largest publicly available contiguous dataset available in genomics for any scientific project in the world. Using the research schooner Tara and modern sequencing and state-of-the-art imaging technologies, a multinational team of scientists sampled microscopic plankton at hundreds of sites and depths in all the major oceanic regions. The Tara Oceans Expedition data have been released, but it is a challenge for researchers to access, manipulate, and analyze such large-scale resources. This project creates an Ocean Cloud Commons (OCC), a cloud-based resource and repository allowing researchers to query the Tara Oceans Expedition Data in the cloud; it also makes available comparative metagenomic tools through the Ocean Treasure Box (OTB).The Ocean Cloud Commons and Ocean Treasure Box build upon established partnerships with organizations such as CyVerse Cyberinfrastructure, Agave Platform, OpenCloud, and computing facilities at the Texas Advanced Computing Center. The Ocean Cloud Commons uses an algorithm based on MapReduce to create a comparative metagenomics data resource in a Hadoop big data framework. The OCC can be widely accessed by researchers using tools developed in the Ocean Treasure Box and implemented as Apps in the CyVerse Cyberinfrastructure. Specifically, OTB tools deploy and compute on OCC data in OpenCloud via the Agave Platform and Developer API from CyVerse. Taken together, the OTB tools and OCC data resources enable researchers to address global-scale questions about the distribution of microbes across the sea that affect climate and ecosystem function.This award by the Advanced Cyberinfrastructure Division is jointly supported by the NSF Directorate for Biological Sciences (Division of Biological Infrastructure), and the NSF Directorate for Geosciences.