Brain development during adolescence and the emergence of depression: A longitudinal MRI study.

传统上，精神卫生服务侧重于已确定的疾病。虽然通过注重早期干预和预防，在其他卫生领域取得了重大成果，但在精神卫生领域，由于无法预测谁可能继续发展为严重的精神障碍，这种做法受到了限制。这项研究将为了解在青春期早期的关键阶段发生的风险过程提供关键信息，因此将对我们了解早期干预和预防策略的目标和对象做出根本性的贡献。

Traditionally mental health services have focused on established disorders. Whilst significant gains in outcomes have been obtained in other areas of health by focusing on early intervention and prevention, in the mental health field this approach has been limited by the inability to predict who is likely to go on to develop serious mental disorder. This study will provide critical information for understanding the risk processes that are operating during the critical phase of early adolescence, and will therefore make a fundamental contribution to our understanding of who, and what, to target in early intervention and prevention strategies.