The impact of Drosophila's endogenous clock on fitness: Influence of light (day length), temperature and nutrition (C05+)

本研究的目的是阐明果蝇的昼夜节律时间保持系统对适应性的重要性。我们将继续对周期（per）突变体的研究，以测试过快的生物钟（pers）、过慢的生物钟（perl）或缺乏生物钟（per01）对寿命和健康的影响。特别是，我们的目标是解释明显的寿命较短，较低的健身的每突变体的竞争实验中发现的第一个资金期间，通过调查他们的新陈代谢，他们的表皮碳氢化合物的配置文件，并通过研究他们的交配偏好。

The aim of this project is to elucidate the importance of the circadian time keeping system for fitness in the model species Drosophila melanogaster. We will continue our studies on period (per) mutants to test the consequences of an either too fast circadian clock (pers), a too slow circadian clock (perl) or an absent circadian clock (per01) on lifespan and fitness. In particular, we aim to explain the apparent shorter life span and lower fitness of the per mutants in competition experiments found in the first funding period by investigating their metabolism, their cuticular hydrocarbon profiles and by studying their mating preferences.