High-Performance Panoptic Mass Spectrometry for Electrocatalytic Reaction Screening

在这个由化学结构、动力学和机理- b和化学测量和成像项目资助的项目中，俄亥俄州立大学化学和生物化学系的Abraham Badu-Tawiah教授正在开发一种新的电催化筛选平台，用于碳碳双键的选择性反应（氧化）。该项目旨在确定能够选择性合成高价值精细化学品的电催化条件。教育和推广活动的目的是直接影响学生在早期阶段（K-12）的教育经历。该项目很好地向学生——包括在STEM领域代表性不足的群体——介绍跨学科科学。大多数非均相电催化剂是氧化物或分散在氧化物载体上的金属。传统上，氧化物合成和随后的反应性筛选分别在两个独立的实验中进行。本项目的目标是将原位氧化合成和催化反应筛选结合到单一实验步骤中的一体化泛光系统。该研究涉及开发一种多模态、封闭的纳米电喷雾系统，用于原位制备电催化剂和随后实时修改反应环境。采用非惰性金属电极对烯烃电氧化制备几种重要的活性化学中间体进行了阳极反应筛选研究。阴极反应筛选展示了在碳氧双键存在下，碳碳双键的选择性还原。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

In this project funded by the Chemical Structure, Dynamics, and Mechanisms-B and Chemical Measurement and Imaging Programs, Professor Abraham Badu-Tawiah of the Department of Chemistry and Biochemistry at Ohio State University is developing a new electrocatalytic screening platform for the selective reactions (oxidation) of carbon carbon double bonds. The project seeks to identify electrocatalytic conditions that enable selective synthesis of high-value fine chemicals. Education and outreach activities are designed to directly impact students in the early stages (K-12) of their educational experience. The project is well-positioned to introduce students - including groups underrepresented in the STEM fields - to interdisciplinary science. The majority of heterogeneous electrocatalysts are oxides or metals dispersed onto oxide supports. Traditionally, oxide synthesis and subsequent reactivity screening occur separately in two independent experiments. This project targets an all-in-one panoptic system that combines in-situ oxide synthesis and catalytic reaction screening into a single experimental step. The research involves the development of a multimodal, contained, nano-electrospray system for the in-situ preparation of the eletrocatalyst and subsequent modification of the reaction environment in real-time. Anodic reaction screening is investigated using the electrooxidation of alkenes by non-inert metal electrodes to produce several important reactive chemical intermediates. Cathodic reaction screening is showcased using the selective reduction of carbon carbon double bonds in the presence of carbon oxygen double bonds.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.