Enhancement of monopartite geminivirus pathogenicity by satellite DNA beta encoded betaC1 protein: the role of host factors

澳大利亚双生病毒的入侵是无法控制的，因为它们由粉虱传播的独特方式。1970年对达尔文的第一次入侵已经蔓延到昆士兰北部的遥远地区。2006年在昆士兰东南部发生的第二次火灾估计给园艺业造成了5亿美元的损失。我们价值20亿美元的棉花产业正受到来自南亚的棉花卷曲病的威胁，在南亚，DNA beta增强了病毒的复制和疾病的严重性。DNAβ病毒有可能携带几种不同的双生病毒进入澳大利亚，并通过合并感染传播到其他国家，这就需要对DNAβ病毒的检测和致病机制进行研究。

Australian incursions of geminiviruses are uncontrollable due to their unique mode of spread by whiteflies. The first incursion in Darwin in 1970 has spread to Far Northern Queensland. The second in SE Queensland in 2006 is estimated to cause $500 million loss to horticulture. Our $2 billion cotton industry is threatened by cotton leaf curl diseases from South Asia, where DNA beta enhances virus replication and disease severity. DNA beta has the potential to enter Australia with several different geminiviruses and to spread into others by co-infection, which requires research on detection and pathogenesis of DNA beta.