Role of plant host factors in the replication and pathogenesis of Tomato leaf curl virus (TLCV)

植物宿主因子在番茄曲叶病毒（TLCV）复制和发病机制中的作用

• 批准号: DP0556930
• 负责人: Prof John Randles
• 金额: $ 15.96万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0556930
• 关键词: Role; plant; host; factors; replication

Geminivirus infection is an emerging problem in the Australian tomato growing industry which is currently worth ca.A$200m annually. Knowledge gained from this research will have direct benefit in safeguarding this industry by providing an insight into geminivirus replication and identifying molecular targets for virus control. More generally, the technology developed through this study will contribute to our basic understanding of virus replication in plants with a view to controlling virus diseases by direct molecular intervention with specifically engineered tools. We foresee potential industrial applications.

双子星病毒感染是澳大利亚番茄种植业的一个新问题，目前每年价值2亿澳元。从这项研究中获得的知识将通过提供对双病毒复制的洞察和确定病毒控制的分子靶点，直接有利于保护该行业。更广泛地说，通过本研究开发的技术将有助于我们对植物病毒复制的基本了解，以期通过特定工程工具的直接分子干预来控制病毒疾病。我们预见到潜在的工业应用。