Engineering Articular Cartilage with Zonal Structure and Function

该项目涉及促进和保持良好健康的国家研究优先事项，特别是优先目标--健康老龄化、富有成效的老龄化。骨关节炎是最常见的软骨相关疾病，每年影响近140万澳大利亚人，导致每1000名澳大利亚人中就有2人接受全关节置换。随着人口老龄化，软骨损伤的发生率和对澳大利亚健康和经济的影响预计将增加。这项工作导致了针对Frontier Technologies的新型软骨工程技术平台的开发，从而为将这项技术推向国际市场奠定了基础。

This project addresses the National Research Priority of Promoting and Maintaining Good Health and specifically the Priority Goal of Ageing well, ageing productively. Osteoarthritis, the most common cartilage-related disease, affects nearly 1.4 million Australians, resulting in 2 in 1000 Australians undergoing total joint replacement, annually. The incidence and impact of cartilage damage on the Australian health and economy is expected to increase with the ageing population. This work leads to the development of a novel cartilage engineering technology platform that addresses Frontier Technologies and will thus provide the foundation for translation of this technology to the international marketplace.