Enhancing immunogenicity of DNA vaccines by targeted delivery to antigen presenting cells.

疫苗已被证明是预防感染的最有效手段之一，也有望成为癌症的治疗方法。然而，能够提供预防多种感染的疫苗的有效技术范围有限。基于DNA的疫苗很有吸引力，因为它们相对容易生产，可以对抗多种感染。然而，DNA疫苗对感染的保护往往很差。该项目将探索澳大利亚开发的一项独特技术，该技术将大大提高DNA疫苗对多种疾病的有效性。

Vaccines have proven to be one of the most effective means of preventing infection and also provide promise as a treatment for cancer. However, the range of effective technologies that make possible the delivery of vaccines that can protect against a broad range of infections is limited. DNA based vaccines are attractive because they are relatively easy to produce against a wide range of infections. However, DNA vaccines often provide poor protection against infections. This project will explore a unique technology developed in Australia and that will greatly improve the effectiveness of DNA vaccines against a broad range of diseases.