Harnessing innate immunity to mitigate bovine respiratory disease

利用先天免疫减轻牛呼吸道疾病

• 批准号: DP200102090
• 负责人: Prof David Jackson
• 金额: $ 40.97万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-06-03 至 2023-06-02
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102090
• 关键词: Harnessing; innate; immunity; mitigate; bovine

Bovine Respiratory Disease (BRD) is the most significant health problem faced by the beef industry worldwide, causing economic losses of up to $40 million annually in Australia alone. This Project aims to assess an immunostimulant for its ability to induce resistance to infection with bovine respiratory viruses associated with BRD. The Project is expected to generate fundamental new knowledge in veterinary virology. Expected outcomes include scholarly publications. The Project will provide significant benefits, such as advances to fundamental knowledge, training of higher research degree students and proof-of-concept data to promote collaborations with commercial partners to develop novel treatment strategies to limit BRD.

牛呼吸道疾病（BRD）是全球牛肉行业面临的最严重的健康问题，仅在澳大利亚每年就造成高达4000万美元的经济损失。本项目旨在评估一种免疫刺激剂诱导抵抗与BRD相关的牛呼吸道病毒感染的能力。该项目有望在兽医病毒学方面产生新的基础知识。预期成果包括学术出版物。该项目将带来显著效益，如基础知识的进步、更高研究学位学生的培训和概念验证数据，以促进与商业伙伴的合作，制定限制BRD的新治疗策略。