I-Corps: Catalytic Porous Organic Polymers

该I-Corps项目更广泛的影响/商业潜力是开发催化材料，使包括药品和染料在内的高价值材料的生产更加高效和绿色。 这些提出的催化剂可以再循环或长时间使用，并且容易与最终产品分离，这简化了这些材料的制造。此外，所提出的材料通过利用可提供溶液样反应性的多孔有机聚合物而具有优点，以及具有负载型表面固定化催化剂的优点。 可回收和易于分离的联合收割机结合起来，创造了可用于传统或新兴生产方法并降低生产成本的系统。这个I-Corps项目是基于新一代具有高度内部自由体积的聚合物所实现的催化新概念的发展。 这些提出的聚合物具有高度的孔隙率，并且通过将非顺应性3D单体直接融合到聚合物主链中的分子水平设计来产生。 聚合物结构是模块化的，并且可以包括能够进行由光促进的反应的结构，所述反应氧化还原化合物（光氧化还原反应性），以及热化学金属催化反应。 催化聚合物可以与磁性无机磁性颗粒、反应器的玻璃侧壁、搅拌涡轮机或管道表面结合。 催化位点周围的聚合物结构和口袋可以产生选择性和高数量的转换。 在光氧化还原催化材料的情况下，聚合物显示出比溶解在溶液中的分子催化剂高得多的速率，这是由于它们的激子和电荷传输能力。该奖项反映了NSF的法定使命，并已被认为是值得通过使用基金会的智力价值和更广泛的影响审查标准进行评估的支持。

The broader impact/commercial potential of this I-Corps project is the development of catalytic materials that will enable the more efficient and green production of high value materials including pharmaceuticals and dyes. These proposed catalysts may be recycled or used for extended periods and are easily separated from the final products, which simplifies the manufacturing of these materials. In addition, the proposed materials materials have an advantage by making use of porous organic polymers that may provide solution-like reactivities as well as the advantages of a supported surface immobilized catalyst. The recyclable and ease of separation combine to create systems that may be used in conventional or emerging production methods and lower production costs. This I-Corps project is based on the development of new concepts in catalysis enabled by new generations of polymers with high degrees of internal free volume. These proposed polymers have high degrees of porosity and are created by molecular level designs that fuse non-compliant 3D monomers directly into the polymer backbone. The polymer structures are modular and can include structures capable of reactions that are promoted by light that oxidize of reduce compounds (photoredox reactivity), as well as thermochemical metal catalyzed reactions. Catalytic polymers can be bound to magnetic inorganic magnetic particles, glass sidewalls of reactors, on stirring turbines, or on the surfaces of tubing. The polymer structures and pockets around the catalytic sites can produce selectivity and high numbers of turnovers. In the case of photoredox catalytic materials, the polymers display much higher rates than molecular catalysts dissolved in solution, as a result of their excitonic and charge transporting abilities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.