Transcriptional regulation of erythropoiesis

这项提议的主要预期结果将是开发一条研究转录因子在基因组水平上如何工作的管道。在前沿技术、促进和保持良好健康方面，将会有国家利益。在人类血液疾病测试的开发、针对遗传和退行性疾病中转录因子异常活性的药物的未来设计方面将会有具体的结果。此外，还将在布里斯班和宾夕法尼亚州研究团队之前的合作基础上建立一座强大的桥梁，这将促进澳大利亚博士和博士后科学家的高级教学和培训。

The major expected outcome from this proposal will be development of a pipeline for the study of how transcription factors work at a genome level. There will be national benefit in the areas of Frontier Technologies, and Promoting and Maintaining Good Health. There will be specific outcomes with respect to development of tests for human blood diseases, future design of drugs to target the aberrant activities of transcription factors in genetic and degenerative diseases. Also, a strong bridge will be built upon the previous collaborations of the research teams in Brisbane and Pennsylvania, which will facilitate advanced teaching and training of Australian PhD and post-doctoral scientists.