Neurotrophic Active Natural Products: Total Synthesis and Biological Evaluation of Neovibsanins A and B, and Analogues

促进神经突生长的新化学实体（候选药物）对人类具有重大影响，因为它们具有修复受损或生长替代神经细胞的真正潜力，受神经和中枢神经系统（CNS）退行性疾病（如阿尔茨海默氏病、帕金森病、亨廷顿病等）的影响。这一科学努力将为潜在的生物和临床应用揭示像分子这样的新药，从而帮助很大一部分患有这些使人衰弱的疾病的澳大利亚人。

New chemical entities (drug candidates) that promote neurite outgrowth have significant ramifications to mankind as they have real potential to repair damaged, or grow replacement, nerve cells affected by neuro and central nervous system (CNS) degenerative disease (e.g. Alzhiemer's, Parkinson's, Huntington's etc). This scientific endeavour will reveal new drug like molecules for potential biological and clinical application, thereby assisting a substantial proportion of Australians suffering from these debilitating diseases.