Mimicking the function of DNA: A novel approach for the synthesis of well-defined metallopolymers

天然材料可以具有各种不同的有趣特性。这些特性通常与预定义的蛋白质结构相关。制造（生物合成）这种高度有序分子的基本信息编码在DNA中。蛋白质生物合成过程是指蛋白质的生物合成过程，其目的是为了达到一定的目的而控制蛋白质的合成，本研究旨在模拟蛋白质生物合成的概念，制备结构确定的配体聚合物及其相应的金属聚合物。为此，将制备代表编码信息的含配体模板。一个高度选择性和正交的结合事件将导致预组织的系统，允许制备含配体的寡聚体。这些部分随后可以使用逐步增长或链增长聚合技术容易地转移到聚合物中。最后，与不同金属盐的络合将导致在所得大分子内形成以高度组织为特征的金属聚合物。所获得的聚合物应进行详细研究。一个特别的重点将是分子结构，此外，在金属聚合物的组织。最后，这种分析应能够阐明结构与性能的关系，并应指向一个新的和先进的金属聚合物的制备方法。

Natural materials can feature a large variety of different interesting properties. Those properties are often associated with a predefined protein structure. The basic information for the fabrication (biosynthesis) of such highly ordered molecules is encoded in the DNA. The process called protein biosynthesis enables the synthesis of these proteins in a controlled manner for a certain purpose.This proposal aims to mimic the concept of the protein biosynthesis in the preparation of structurally defined ligand containing polymers as well as their corresponding metallopolymers. For this purpose, ligand-containing templates will be prepared, which represent the encoded information. A highly selective and orthogonal binding event would result in preorganized systems allowing the preparation of ligand-containing oligomers. Those moieties can later easily be transferred into polymers using either a step-growth or a chain-growth polymerization technique. Finally, the complexation with different metal salts will result in the formation of metallopolymers featuring a high degree of organization within the resulting macromolecule. The obtained polymers should be studied in detail. A particular focus will be the molecular structure and, furthermore, the organization within the metallopolymers. Finally, this analysis should enable to elucidate structural-property relationships and should direct to a new and advanced preparation methods of metallopolymers.