Asymmetric Synthesis and Biological Evaluation of Bioactive Alkaloids and their Analogues

我们建议开发创新的方法来制备具有生物活性的天然产物及其类似物，作为新的和更安全的治疗药物和农业化学品。该项目将对提高合成有机化学的基础知识作出重要的科学贡献，并为澳大利亚作为一个知识型经济的发展作出贡献。所开发的方法和产品可能具有潜在的医药和农业应用，该国将来可以从中受益。该项目将帮助培养技术人才，这些人才可能在未来开发出创新成果，特别是在澳大利亚发展中的制药和生物技术行业。

We propose to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The methodology and products developed may have potential pharmaceutical and agricultural applications from which the country could benefit from in the future. This project would help developed skilled people that may develop innovative outcomes in the future, especially in the developing pharmaceutical and biotechnology industries in Australia.