Interactions Between Bacteria of the Roseobacter Group and Marine Algae via Sulfur Metabolites (B07*)

在第三个应用期内，将研究Rosefilm组细菌与其他生物体通过硫代谢物（如托泊二硫乙酸（TDA）和2，3-二羟基丙烷-1-磺酸盐（DHPS））的相互作用以及N-酰基高丝氨酸内酯（阿勒）合成的机制。将完成阐明TDA生物合成中所有酶的工作，另外两类DMSP裂解酶/水解酶和DMSP去甲基化途径的酶将被表征，并在体外研究DHPS降解。

During the third application period the interactions between bacteria of the Roseobacter group with other organisms via sulfur metabolites such as tropodithietic acid (TDA) and 2,3-dihydroxypropane-1-sulfonate (DHPS) will be studied as well as mechanisms of N-Acylhomoserine lactones (AHL) synthesis. Work on elucidating all enzymes in TDA biosynthesis will be completed, two further classes of DMSP lyases/hydrolases and enzymes of the DMSP demethylation pathway will be characterized and DHPS degradation studied in vitro.