The ventilatory effect of the percutaneous electrical stimulation of phrenic nerve

本研究的目的是明确经皮电刺激和磁刺激对膈神经的换气效果，并探讨其作为一种人工呼吸机的临床应用的可能性。产生最大潮气量的电刺激频率和脉宽的最佳值分别为50~150赫兹和0.5~1ms。同样，经皮磁刺激也可以产生相同的通风效果。可以制作出与传统流量计相似的超小型流量计。长期经皮磁刺激对颈部除膈神经外的其他神经的生物学影响有待进一步研究。

The purpose of this study is to clarify the ventilatory effect of percutaneous electrical as well as magnetic stimulation of phrenic nerve and to investigate the possibility of clinical application as an artificial ventilator.The ventilatory effects were evaluated mainly by tidal volume and transdiaphragmatic pressure. The optimum values for electrically stimulating frequency and pulse width to produce the maximum tidal volume were 50-150Hz and 0.5-1m sec. respectively.The same ventilatory effects could also be painlessly generated by the percutaneous magnetic stimulation as well.The very small sized flowmeter could be fabricated and have the similar characteristics to conventional ones. The further research on the biological influences to the other nerves except phrenic nerve at neck in the case of longterm percutaneous magnetic stimulation should be necessary to study.