The Development of Human Engineering Therapeutic Equipments for Respiratory Muscle Fatigue

呼吸肌疲劳人体工程治疗仪的研制

• 批准号: 63870035
• 负责人: KONNO Kimio
• 金额: $ 4.42万
• 依托单位: Tokyo Women's Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B).
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63870035/
• 关键词: Respiratory muscle fatigue; Respiratory failure; Portable oxygen concentrator; Portable-demand type negative pressure ventilator; Respiratory muscle; 携帯用酸素濃縮装置; 携帯用換気補助装置

Efforts were made for 3 years from 1988 to 1990 to develop portable oxygen concentrator and a portable-demand type negative pressure ventilator as human engineering therapeutic equipment in order to improve the qualith of life for patients with respiratory muscle fatigue. A clinical study on concurrent use of these medical equipments showed that they were useful for the home care to patients with chronic respiratory failure due to respiratory muscle fatigue.1. portable oxygen concentratorA ventilatory synchronizer with a built-in capacitance-type pressure sensor was included. SaO_2 levels were improved as a result of increase in the constant flow from the concentrator.2. portable-demand type negative pressure ventilatorThis equipment consists of a chest wall suit, ventilatory synchronizer and the driving system. The power source may be AC, DC batteries or automobile batteries. It can be easily carried using a shoulder strap or the attached carrier (total weight : about 6kg). The effica … More cy of this ventilator was evaluated in the patients with chronic respiratory failure. Beneficial effects were observed on parameters such as the degree of dyspnea (Borg score), SaO_2, and Vo_2/V_E.3. Efficacy of concurrent use of the portable oxygen concentrator and the portable-demand type negative pressure ventilatorEffects of 1-hr inhalation on SaO_2 was evaluated for the patients with chronic respiratory failure using firstly the portable oxygen concentrator alone. Secondly effects of the concurrent use of the portable oxygen concentrator and the portable-demand type negative pressure ventilator with a ventilatory synchronizer were then evaluated in the same patients. Greater improvement of SaO_2 was observed after than before use of the portable ventilator, indicating the presence of synergistic effects of the two medical equipment.The portable oxygen concentrator was approved as a medical equipment under the Pharmaceutical Affairs Law by the Japanese Ministry of Health and Welfare on October 17, 1990. An patent application for the portable-demand type negative pressure ventilator was published by the Japan Patent Office on December 13, 1990. Less

1988年至1990年历时3年，开发出便携式制氧机和便携式按需式负压呼吸机作为人体工程治疗设备，以提高呼吸肌疲劳患者的生活质量。同时使用这些医疗设备的临床研究表明，它们对于呼吸肌疲劳导致的慢性呼吸衰竭患者的家庭护理是有用的。 1．便携式制氧机包括带有内置电容式压力传感器的通气同步器。由于浓缩器恒定流量的增加，SaO_2水平得到改善。2．便携式按需式负压呼吸机该设备由胸壁服、通气同步器和驱动系统组成。电源可以是交流、直流电池或汽车电池。可以使用肩带或附带的背带轻松携带（总重量：约6公斤）。该呼吸机的疗效在慢性呼吸衰竭患者中进行了评估。观察到对呼吸困难程度（Borg 评分）、SaO_2 和 Vo_2/V_E.3 等参数的有益影响。便携式制氧机与便携式按需式负压呼吸机同时使用的疗效首先单独使用便携式制氧机，评估慢性呼吸衰竭患者1小时吸入对SaO_2的影响。其次，在同一患者中评估同时使用便携式制氧机和带有呼吸同步器的便携式需求型负压呼吸机的效果。便携式呼吸机使用后的SaO_2比使用前有更大的改善，表明两种医疗设备存在协同效应。便携式制氧机于1990年10月17日被日本厚生省批准为药事法下的医疗设备。日本专利局于1990年12月13日公布了便携式需求型负压呼吸机的专利申请。少

项目成果

T.Akatsu,J.Ishihara,Y.Wakai,T.Watanabe,M.Yamaguchi,T.Takubo,K.Yoshino.K.Konno,and T.Takizawa.: "Development and clininl application of a portoble oxygen Conlentrntor." Frontiers Med.Brol.Engng. 2. 293-301 (1990)

T.Akatsu、J.Ishihara、Y.Wakai、T.Watanabe、M.Yamaguchi、T.Takubo、K.Yoshino.Konno 和 T.Takizawa.：“便携式制氧机的开发和临床应用。”

T. Hirano, Y. Sugiyama, K. Yoshino and K. Konno: "Improvement of Magnetpneumometer" Frontiers Med. Biol. Engng.

T. Hirano、Y. Sugiyama、K. Yoshino 和 K. Konno：“磁力呼吸计的改进” Frontiers Med。

阿久津 敏恵,渡辺 敏恵,金野 公郎: "酸素濃縮装置" 肺と心. 37. 27-33 (1990)

Toshie Akutsu、Toshie Watanabe、Kimiro Konno：“氧气浓缩器”肺和心脏。 37. 27-33 (1990)

金野公郎,杉山吉彦,阿久津敏恵,飛田渉,野城真理,諏訪邦夫,新田澄郎: "呼吸ケア-の新展開" 医用電子と生体工学. 21. 41 (1989)

Kimiro Konno、Yoshihiko Sugiyama、Toshie Akutsu、Wataru Tobita、Mari Nojo、Kunio Suwa、Sumio Nitta：“呼吸护理的新发展”医疗电子和生物工程 21. 41 (1989)。

金野公郎: "呼吸筋のエネルギ-調節" 人工呼吸. 6. 6 (1989)

Kimiro Konno：“呼吸肌的能量调节”人工呼吸。6. 6 (1989)。