Investigating the influence of two major Ionotropic Receptors on Aedes aegypti mosquito acoustic behaviors

我已经成功地产生了一个IR21a纯合负性突变体，并研究了温度对男性突变体听力系统的影响。没有发现听力敏感度的显著变化，尽管这个突变体似乎表现出湿度感觉的改变，而不是温度感觉。有趣的是，IR21a在伊蚊中的分布似乎与其他蚊子物种不同，这可能表明功能发生了变化。我目前正在产生一个IR25a纯合子负突变，以便我也可以对这条线进行分析。我还将我的研究扩展到我在耳朵组织中识别的其他离子亲和性受体，以调查它们在听力热敏中的潜在作用。

I have successfully generated an IR21a homozygous negative mutant and investigated the influence of temperature on male mutant hearing systems. No significant changes in hearing sensitivity have been found, though this mutant appears to demonstrate altered humidity sensation rather than thermosensation. Interestingly, the distribution of IR21a in Aedes mosquitoes appear distinct from other mosquito species, potentially suggesting changes in function.I am currently generating an Ir25a homozygous negative mutant so that I can also perform assays on this line. I am also expanding my research into other Ionotropic Receptors which I have identified in ear tissues to investigate their potential role in hearing thermosensitivity.