Genetics of Postmenopausal Bone Loss

在我们老龄化的社会中，骨丢失的主要后果是骨折。对于50岁的女性来说，终生罹患骨质疏松性骨折的风险是50%。这些骨折的后果可能包括预期寿命缩短、医疗护理时间延长和丧失独立性，在老龄化人口中具有深远的社会经济影响。这项拟议的研究提供了一个独特的机会来检验遗传因素对绝经后骨质疏松症的贡献。

The major consequence of bone loss in our ageing society is fracture. At 50 years for women, the lifetime risk of sustaining an osteoporotic fracture is 50%. The consequences of these fractures, which can include reduced life expectancy, prolonged medical care, and loss of independence, have a profound socioeconomic impact in an ageing population. The proposed study offers a unique opportunity to examine the contribution of genetic factors to postmenopausal osteoporosis.