A Pathological Study of Epithelium in Severe Cornero-Conjunctival Diseases.

眼表疾病的结膜组织侵袭是最难预防的并发症，本研究采用角膜上皮细胞，特别是角膜缘细胞，进行体外培养。结果表明，利姆布斯附近的细胞不仅分裂活跃，而且迁移也比其他部位的细胞活跃。此外，颞叶周围的细胞可靠地显示了这种趋势。从这个角度来看，角膜缘组织实验移植到新生血管角膜。结果表明，牛磺酸和透明质酸对角膜上皮细胞的再生效果与角膜上皮细胞的再生效果相当，实验证实了牛磺酸和透明质酸对角膜上皮细胞的再生作用，为临床应用提供了可能。结膜瓣对严重间质病变的治疗效果较好，达到了预期的效果;快速上皮再生，免疫学研究发现结膜内存在CALT，并对接种的淋巴细胞进行了组织学观察，基质细胞对异物的反应和粘蛋白的详细情况，以及角膜上皮细胞对异物的反应和粘蛋白的反应，为我们提供了与眼表防御系统相关的最重要的信息。还研究了表面上皮上的层。

Invasion of conjunctival tissue of ocular surface disorders has been known as the most difficult complication to prevent its progress.In this study, corneal epithelial cells especially limbal cells, were incubated. And it became clear that not only the segmentation but also the migration of the cells near the limbus were much more active than those cells from other portions. Moreover, those cells from the temporal periphery reliably showed this tendency. From this point of view, limbal tissue were experimentally transplanted to the neovascularised corneas. The results showed the excellent re-epithelization as likely as corneal epithelial cells.The effects of epithelial wound healing of Taurine and hyaluronic acid were experimentally certified and those results led us the possibility of clinical use with these drugs. Conjunctival flapping to the severe stromal disorders used to show the good enough results which we expected ; Quick re-epithelization, settlements of inflammation.The most remarkable information related to the defense system in ocular surface was brought us by the finding of CALT in conjunctiva with immunological studies in which the inoculated lymphocytes were observed histologically.The stromal cell reactions to the foreign bodies and the details of mucin layers on the superficial epithelium were also studied.