Arterial blood pressure responses to mild exercise, maximum aerobic power, and reflexes of baroreceptors in healthy young persons with genetic disposition of hypertension

为了了解具有遗传倾向的正常青年人发病前高血压的工作者和/或预测者，本研究调查了人类受试者对轻度运动、最大有氧功率和高、低压力感受器反射的动脉血压反应之间的关系。主要工作是建立间接（无血）方法如何分别和同时刺激颈动脉窦中的高压感受器和心肺部分中的低压感受器。二是如何确定选题的特点。实践研究已根据以下主题进行：1。作为方法学研究，A.开发刺激高压感受器的系统，B。基础调查确定压力负荷的高和低压力感受器，C。领域选择主体; 2.知道血压对直立运动的反应，A.血压对运动的反应随运动量的增加而增加 ...更多信息 健康青年人的阶跃负荷与性格，B。体育锻炼对血压对休息和运动的反应的影响，C。生活方式对中年气质人群血压对休息和运动反应的影响根据研究结果，得出结论：刺激心肺部压力感受器的下体负压负荷上限为-40 mmHg，刺激颈动脉窦压力感受器的颈部吸气压力上限为-50 mmHg，轻度直立运动负荷为50瓦，受试者将排除任何具有比正常健康人高的体脂百分比或最大有氧能力的人，即使他们具有高血压的遗传倾向。在前人研究结论的基础上，进行了两项研究：1.在10天卧床休息期间，具有高血压遗传倾向的正常健康年轻人的觉醒血压和心率的变化; 2.轻度直立运动时的动脉血压反应和青年人高、低压力感受器反射的敏感性。研究发现，有此倾向的正常健康人对轻度直立运动的血压反应性高于无此倾向的青年人，心肺部低压力感受器对交感神经活动调节的抑制作用强于无此倾向的青年人，而颈动脉窦高压力感受器的抑制作用与无此倾向的青年人相似。少

To know workers and/or predictors of hypertension before its' onset in normal young persons with the genetic disposition, the present study has investigated relations between arterial blood pressure responses to mild exercise, maximum aerobic power, and reflexes of high- and low-baroreceptors in human subjects.In 1990, a main work was on establishing indirect (bloodless) methods how to make separately and simultaneously stimulating high-baroreceptors in the carotid sinus and low- baroreceptors in the cardio-pulmonary part. Another was how to decide characteristics of subjects selected. The practical studies have been performed according to following themes ; 1. as methodological studies, A. developing a system stimulating the high-baroreceptors, B. basal investigation determining pressure loads on the high- and low-baroreceptors, C. realm selecting subjects, and 2. as knowing blood pressure responses to upright exercise, A. blood pressure responses to exercise increasing with step-by-s … More tep loads in healthy young persons with the disposition, B. effects of physical training on blood pressure responses to rest and exercise, C. effects of life styles on blood pressure responses to rest and exercise in middle aged persons with the disposition. Depending on the results in the studies, it has been concluded that the upper-limit of lower body negative pressure load to stimulate baroreceptors in cardio-pulumonary part is a -40mmHg, upper-limit of neck suction pressure to stimulate baroreceptors in carotid sinus is a -50mmHg, a load in mild upright exercise is a 50watts, and the subjects would exclude any persons who had higher % body fat or higher maximum aerobic power than the levels in normal healthy persons even though they held the genetic desposition of hypertension.In 1991, followed in the conclusions given by the previous studies, two studies have been performed ; 1. changes in awakening blood pressure and heart rate during 10 days bed-rest in normal healthy young persons with genetic disposition with hypertension, and 2. arterial blood pressure responses during mild upright exercise and sensibilities of high- and low-baroreceptors reflexes in the young persons. In the studies, it has been found that in normal healthy persons with the disposition the blood pressure response to mild upright exercise is higher, and the inhibitory effect of low-baroreceptors in the cardio-pulmonary part on regulating sympathetic nervous activity is stronger as compared with young persons without the disposition, but the the effect of high-baroreceptors in the carotid sinus is similar. Less