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High Content Microscope (automated)

High Content Microscope (automated)
高内涵显微镜(自动)
批准号:
436453180
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
德国
项目类别:
Major Research Instrumentation
财政年份:
2020
资助国家:
德国
项目状态:
未结题
起止时间:
2019-12-31 至 --

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中文摘要
翻译
该表型分析仪配备了高容量成像系统,可高通量测量自光合浮游生物及其相互作用物种(如轮虫、原生生物和病毒以及异养原生生物)的一系列表型特征。这为描述和机械地研究水生浮游生物和微生物群落之间的相互作用开辟了全新的可能性。具体而言,表型分析单元的设置允许同时测量数百个个体基因型和重复的性状以及几个性状。拟议的表型单位是必不可少的,我们的工作的生态和进化的变化,特别是对检测的变化,随着时间的推移,性状变异和协变,这需要同时记录的几个性状的个体细胞或个体动物内的机械理解。表型分析单元的高通量允许以统计学稳健的方式记录不同相互作用物种的性状的表征。康斯坦茨大学没有这样的表型分析单位。
英文摘要
The phenotyping unit with a high-content imaging system is specifically designed for the high-through put measurement of a suit of phenotypic traits in auto-photosynthetic plankton organisms and their interacting species such as rotifers, protists and viruses, as well as heterotrophic protists. This opens up completely novel possibilities for describing and mechanistically investigating the interactions within aquatic plankton and microbial communities. Specifically, the set-up of the phenotyping unit allows measuring traits of hundreds of individual genotypes and replicates simultaneously and several traits. The proposed phenotyping unit is indispensable for our work on the mechanistic understanding of the ecological and evolutionary changes within communities, specifically for the detection of changes in trait variation and covariation over time, which requires the concurrent recording of several traits of individual cells or individual animals. The high throughput of phenotyping unit allows the characterization of traits of different interacting species be recorded in a statistically robust manner. Such a phenotyping unit is not available at the University of Constance.
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