Fluid Dynamics of Circulation: Focus on the Kidney

在澳大利亚，大约30%的成年人患有高血压，这是心脏病的主要危险因素，约占所有死亡人数的40%。肾循环问题可能是导致高血压的因素。在我们治疗或预防高血压之前，需要详细了解肾循环的水力学特性，我们对此了解有限。我们将确定血管的大小，结构和几何形状如何影响肾脏的功能。这将导致预测模型，以帮助设计和解释生理研究和高血压的斗争。它还将有助于正在进行的生物人工肾的开发，以取代目前的透析系统。

In Australia, about 30% of adults have hypertension, a major risk factor for heart disease, accounting for about 40% of all deaths. Problems in renal circulation are likely factors leading to hypertension. A detailed understanding of the renal circulation, of whose hydraulic characteristics we have limited knowledge, is required before we can cure or prevent hypertension. We will determine how the size, structure and geometry of the blood vessels influence the function of the kidney. This will lead to predictive models to aid the design and interpretation of physiological studies and the combat of hypertension. It will also help in the ongoing development of bioartificial kidneys to replace present dialysis systems.