Study on demyelinating lesions in human demyelinating disorders

为了研究人类脱髓鞘疾病的脱髓鞘过程，我们利用个人计算机系统对多发性硬化症病变进行了三维分析。多发性硬化病变的三维显示病变与脑室或相当大的血管有明确的解剖关系。然而，在分析脱髓鞘病变与毛细血管之间的三维关系以及浸润性炎症细胞的分布方面存在一些技术困难。我们利用计算机断层图像和脑血管造影数据，将该三维分析系统应用于脑肿瘤。以下结果显示了该系统在脑肿瘤手术治疗中的应用前景。a)该系统显示了脑肿瘤的三维显示，显示了肿瘤与其他组织的清晰解剖关系。b)该系统能在任意点或任意放大下分析肿瘤，并能显示任意水平的肿瘤横切面。c)该系统能在肿瘤横切面上进一步给出肿瘤与血管或脑室的解剖关系。d)由于个人计算机是便携式设备，所以该系统的数据是可用的。在外科手术和手术室检查期间。

To study the demyelinating process of human demyelinating diseases, we analysed multiple sclerosis lesions three-dimentionally using the personal computer system. Three-dimentional display of multiple sclerosis lesions showed clear anatomical relationship between the lesions and the ventricles or fairly large vessels. However, there were some technical difficulties in analysing a three-dimentional relationship between the demyelinated lesion and capillaries, and the distribution of infiltrating inflammatory cells.We applied this three-dimentional analysis system to brain tumors, using data of computed tomographic images and those of cerebral angiography. The following results show a promising usage of the system for surgical treatment of brain tumors.a) This system showed three-dimentional displays of brain tumors demonstrating clear anatomical relationship between the tumor and other tissues.b) This system has facility in analysing the tumor at any points or at any magnification, and in demonstrating displays of transverse section of the tumor at any level.c) This system gave a further anatomical relationship between the tumor and vessels or ventricles at any transverse section of the tumor.d) Since the personal computer is a portable set, the data of this system are available. during a surgical operation and examination in the operation room.