Disulfide Bonds and Protein Folding

这项工作将增进我们对蛋白质折叠的理解，这在生物技术中具有重要意义，对重组蛋白质的商业生产(用于制药和生物医学应用)以及世界各地使用重组技术的数千个研究实验室都有影响。这项研究也可能有助于医学(治疗阿尔茨海默氏症等蛋白质错误折叠疾病的新疗法)，以及膜蛋白质结构生物学。从长远来看，这项工作可以通过专利成果产生经济效益，并将通过发表影响较大的研究论文、为澳大利亚人提供培训以及与国际知名科学家建立联系而使社区受益。

This work will advance our understanding of protein folding, which has important implications in biotechnology, impacting on commercial production of recombinant proteins (for pharmaceutical and biomedical applications) and on 1000s of research laboratories worldwide that use recombinant technologies. This research could also contribute to medicine (new treatments for diseases of protein misfolding like Alzheimer's), and to membrane protein structural biology. This work could yield economic benefits in the long-term through patentable outcomes and will benefit the community by producing high impact research papers, providing training to Australians and forging links with renowned international scientists.