Generations of Organometallic Species by Novel Reduction Reactions and their Applieations to Organic Synthesis

1. 铜酸盐配合物作为还原剂，可直接制备(E)和(Z)乙烯基铜试剂。(Chem.Lett。1994年,437年;Bull.Chem.Soc。Jpn.1994, 67年,1495年)。选择性地制备了功能化烯丙基铜试剂。(J.Chem.Soc。Chem.Commun.1994, 2687)。锰酸盐配合物与α -全酮反应生成亲本酮烯醇酯。利用这些反应可以很好地控制烷基化反应和醛醇反应的区域选择性。(准备)2。研究了氧酰烯丙基硅烷、氨基硅烷、硫甲基硅烷和烷氧氢硅烷的反应性。(J.Organometal.Chem。1994,473, c1；Chem.Lett。1994年,719年;杂原子化学，1994,5,229；四面体通讯。1995,36,571；Bull.Soc.Chim.Fr.1995, 132499)。(J.Organometal.Chem.1995 499155)。3。发现了生成非稳定羰基基的新方法。(J.Am.Chem.Soc。1996年，第118期，印中；Synlett， 1996年出版。)

1. Copper ate-complexes serve as reductants and (E) -and (Z) -vinylcopper reagents can be prepared directly. (Chem.Lett.1994,437 ; Bull.Chem.Soc., Jpn.1994,67,1495.) Functionalized allylcopper reagents were also prepared selectively. (J.Chem.Soc., Chem.Commun.1994,2687.) Manganese ate-complexes react with alpha-holoketones to generate enolates of the parent ketones efficiently. Using these reactions, regioselectivities in alkylation and aldol reaction are controlled perfectly. (in preparation)2. Reactivities of oxiranylallylsilanes, aminosilanes, thiomethylsilanes, and alkoxyhydrosilanes were investigated. (J.Organometal.Chem.1994,473, C1 ; Chem.Lett.1994,719 ; Heteroatom Chem.1994,5,229 ; Tetrahedron Lett.1995,36,571 ; Bull.Soc.Chim.Fr.1995,132,499.) (J.Organometal.Chem.1995,499,155.)3. Novel methods for generation of non-stabilized carbonyl ylids were found. (J.Am.Chem.Soc.1996,118, in press ; Synlett, 1996, in press.)