CNS participation in blood pressure charges at ventrolateral medulla compression of rat

（材料与方法）对34只大鼠进行呼吸机麻醉，调整氧流量使血气和PH值维持在生理范围内。将动物俯卧放置以暴露腹外侧髓质，以便在第ix和第Xth脑神经的腋窝下插入硅胶微球。球囊受压部位如下：a) cl -细胞组右侧腹内外侧髓质（Rt-VLM）出现电解损伤，b)未出现电解损伤的Rt-VLM， c) C1 -细胞组左侧(Lt) -VLM出现电解损伤，d) Lt-VLM未出现电解损伤，e) cl -细胞组Rt-和Lt-VLM出现双侧电解损伤。（结果）球囊膨胀引起的血压升高不仅有左压升高，还有左压升高。在有和没有电解损伤的cl细胞组之间，血压变化也没有明确的差异。（结论）这些大鼠实验结果不支持临床证据，即在左侧第IXth和第Xth脑神经前区动脉环活动后，术前长期高血压得到缓解。

(Materials & Methods)Thirty-four rat were anesthetized under respirator and oxygen flow adjusted to maintain blood gases and PH within physiological limits. The animals were placed prone to expose the ventrolateral medulla to permit insertion of silicone microballon beneath the axilla of the IXth & Xth cranial nerves. The sites of balloon compression were as followings : a) right ventrolateral medulla (Rt-VLM) with an electrolytic lesion at Cl-cell group, b) Rt-VLM without an electrolytic lesion, c) left (Lt) -VLM with an electrolytic lesion at C1 -cell group, d) Lt-VLM without an electrolytic lesion, e) Rt-&Lt-VLMs with bilateral electrolytic lesions at Cl-cell groups.(Results)Balloon inflation caused a significant elevated blood pressure not only Rt but also Lt-side compression. There were also no definite difference in changing blood pressure between with and without an electrolytic lesion at Cl-cell group.(Conclusion)These experimental results using rats did not support the clinical evidence, that was the relief of preoperative long-standing hypertension after the mobilization of an arterial loop on the area anterior to the left IXth & Xth cranial nerves.