Is there the risk of lung cancer in dental staff?

在这项研究中，我们通过测量牙科工作人员肺组织中沉积的各种金属的数量来评估牙科工作人员患肺癌的风险。在一名死于肺癌的牙科技术人员的尸检中，切除了肺组织样本。用热中子放射性分析测定了各种金属的沉积量。对于另外两名死于肺癌的患者和三名死于心脏病的患者，各种金属的定量方法与上文提到的相同。将结果与牙科技师的结果进行了比较。与其他患者相比，这名牙科技师的肺组织中金、银、钴、铬和铜的含量较高。这些金属在牙科合金中的使用量相当大，金、铬被认为是致敏性的，铬也是致癌的。因此，我们建议这些金属对肺部有潜在的不良影响。为了调查…的风险和组织病理学肺癌的更多特征与牙科占位有关，我们在大阪癌症和心血管疾病医学中心共4138例被诊断为携带恶性肿瘤的患者中搜索了各种恶性肿瘤，其中24例是牙科工作人员。41.7%的牙科工作人员和19.7%的非牙科工作人员被诊断为携带肺癌的恶性肿瘤。肺癌、鳞癌、腺癌、大细胞癌和小细胞癌四种组织学分型分别占10.0%、80.0%、0.0%和10.0%，812例患者中分别为35.3%、36.3%、5.8%和18.0%。我们认为，从事牙科工作的人患肺癌的风险很高，其组织类型很可能是腺癌。我们测量了一名牙科工作人员头发中沉积的各种金属的数量。通过热中子放射性分析确定了这些矿样中各种金属的沉淀量。结果与教务长工作人员的结果进行了比较。牙科工作人员的头发中铝、金、钴、铜和钒的含量较高。我们的结果可能表明牙科工作人员有患肺癌的风险。因此，可以敦促提高牙科诊所和实验室的环境标准。较少

In the present study, we assessed the risk of lung cancer in dental staff by measuring the amounts of various metals deposited in the lung tissue of a dental staff. At the autopsy of a dental technician who died of lung cancer, lung tissue samples were excised. The amounts of various metals deposited were determined by thermal neutron radioactive analysis. For two other patients who died of lung cancer and three patients who died of heart disease, various metals were quantitated in the same manner as mentioned above. The results were compared with those from the dental technician. The dental technician's lung tissue proved to have a higher content of the metals Au, Ag, Co, Cr and Cu in comparison with the other patients. These metals are used in dental alloys in considerable quantities, and Au, Cr are considered to be allergenic, and Cr is also carcinogenic. Therefore, we suggest potential adverse pulmonary effects of these metals.In order to investigate the risk and histopathological … More characteristic of lung cancer on pertaining to the dental occupaition, we searched kinds of malignant tumors in a total of 4,138 cases of patients who were diagnosed to be carrying malignant tumor at Osaka Medical Center for Cnacer and Cardiovascular Diseases, of whom 24 were dental staff personnels. 41.7% of dental staff personnels and 19.7% of nondental staff personnels were diagnosed to be carrying the malignant tumor which was identified to be fo the lung cancer. Four histological typing of lung cancer, squamous cell carcinoma, adenocarcinoma, large cell carcinoma and small cell carcinoma were observed in 10.0%, 80.0%, 0.0% and 10.0% respectively out of 10 dental staff personnels and 35.3%, 36.3%, 5.8% and 18.0% respectively out of all 812 patients. We suppose that people engaged in the dental occupation have a high risk of developing lung cancer and its histological typeis highly likely to be of adenocarcinoma.We measured the amounts of various metals deposited in the hair of a dental staff. The amounts of various metals deposited in these sumples were determined by thermal neutron radioactive analysis. The results were compared with those from the deantl staff. The dental staff's hair proved to have a higher content of the metals Al, Au, Co, Cu and V.Our results may suggest that there is the risk of lung cancer in dental staff. Therefor, it might be urged that environmental standards be improved in dental clinics and laboratories. Less