Imaging MS part 3

随着在大学医院Klinikum rechts der Isar（以下简称BayBioMS@MRI）的TUM校园的第二个站点的开放，慕尼黑技术大学（TUM）加强了巴伐利亚生物分子质谱中心（BayBioMS）作为生命科学研究中质谱的中心仪器平台。由于尖端国际研究对质谱技术应用的需求增加，这种扩展已成为必要。通过建立不同研究部门之间的协同作用，我们为TUM的所有科学家提供了更好的关键研究技术。TUM已经为BayBioMS@MRI提供了人员和房间。当前申请的目的是实现BayBaMS@MRI主要设备基础设施。具体而言，TUM打算获得两台具有不同测量技术能力的高分辨率质谱仪，用于蛋白质组学研究，以及一台用于基于质谱的成像应用的高分辨率质谱仪。蛋白质组质谱仪与纳米HPLC系统和移动的MALDI成像源耦合。该组合应用还包含一个自动化样品制备系统，包括离线HPLC和液体处理平台，以及用于数据存储、处理和分析的必要IT基础设施。这些组件共同构成了一个功能单元，多年来，这一概念在Freising的BayBioMS工厂得到了非常成功的应用。该应用基于18个研究小组的具体研究项目。这些项目是未来将通过这一新的基础设施投资支持的众多项目的一个例子。BayBioMS@MRI的主要目标是：1.提供最先进的LC-MS和成像MS设备，以支持最高国际水平的尖端研究。2.通过为我们的用户和合作伙伴提供科学和技术知识，从始至终的项目支持和最佳建议来获得高质量的结果。3.通过举办有关这一现代关键技术的研讨会、讲习班和课程，促进学生、科学家和技术人员的教育和科学专门知识。追求我们自己的创新研究项目，以推进技术方面，如自动化，样品制备，测量技术或数据分析。5.并促进现有的组织结构和科学专业知识之间的联系，在BayBioMS在弗赖辛的TUM校园和新的网站在TUM诊所校园在慕尼黑，以充分利用所有现有的和计划的资源，并产生协同效应。

With the opening of a second site at the TUM campus at the University hospital Klinikum rechts der Isar (in the following referred to as BayBioMS@MRI) the Technical University Munich (TUM) strengthens the Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) as central instrument platform for mass spectrometry in life science research. This expansion has become necessary due to the increased demand for mass spectrometry technology applications in cutting-edge international research. By building on synergies between different research departments we provide improved access to key research techniques for all scientists at TUM.Personnel and rooms for the BayBioMS@MRI have already been provided by the TUM. The aim of the current application is now to realize the BayBaMS@MRI major equipment infrastructure. In detail, the TUM intends to acquire two high resolution mass spectrometers with different measurement technique capabilities for proteomic research and one high resolution mass spectrometer for mass spectrometry based imaging applications. The proteomic mass spectrometers are coupled with nano-HPLC systems and a mobile MALDI imaging source. The combined application also contains an automated sample preparation system consisting of an off-line HPLC and a liquid handling platform as well as the necessary IT infrastructure for data storage, processing and analysis. Together these components form a functional unit and this concept has been used very successfully at the BayBioMS location in Freising for many years.The application is based on concrete research projects from 18 research groups. These projects are an example for the multitude of future projects that will be supported through this new infrastructure investment. Main goals of the BayBioMS@MRI are: 1. To offer access to state-of-the-art LC-MS and Imaging MS equipment in order to support cutting-edge research on the highest international level.2. To obtain high quality results by providing scientific and technical know-how, start-to-end projects support and the best possible advice for our users and collaboration partners. 3. To promote the education and scientific expertise of students, scientists and technical staff by giving seminars, workshops and courses for this modern key technology.4. To pursue our own innovative research projects in order to advance technical aspects like automation, sample preparation, measurement techniques or data analysis.5. And to foster the connection between the existing organization structure and scientific expertise at the BayBioMS at the TUM campus in Freising and the new site at the TUM clinic campus in Munich in order to take full advantage of all existing and planned resources and generate synergies.