Control of Aging by the use of Artificial Organs
Control of Aging by the use of Artificial Organs
批准号:
11480253
负责人:
YAMBE Tomoyuki
金额:
$7.17万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2002
中文摘要
由于老龄化社会不可避免地到来,我们科普老龄化带来的各种疾病,并有必要瞄准健康老年人发挥积极作用的社会。虽然衰老现象也可以被认为是整个身体的变化,但在医学上,它是作为一个内部器官单位疾病的产生。内部器官单位的疾病是各种药物和外科手术的适应。对于已经发展到不可逆转的内部器官功能障碍,移植、人工器官等成为维持生命所不可或缺的。因此,在健康的老龄化社会中,支持高科技医疗(例如人造器官)的可能性很高。它正在成为旧的记忆与共产主义集团的崩溃,长期的斗争,为生存的动物实验的人工心脏进行了应用国家的威望, 关于我们 l在世界各地。从那时起,在世界人工心脏研究者之间就有一种意见。它是“植入人工心脏后动物的衰老是早期的吗?”这是假设说。对于在植入人工心脏后也可被视为促进这种老化的病理生理变化,东京大学提出了“人工心脏综合征”的综合征。在东北大学也进行了与各种人工循环和衰老相关的心血管系统变化的研究。东北大学发育衰老与癌症研究所在教育部科学研究费的试验研究支持下,实施了“作为衰老促进模型的人工心脏动物的非线性分析”的研究课题。建立了人工心脏慢性老化动物模型。根据这一结果,1999年至2003年,日本文部科学省进行了科学研究成本基础研究“通过人工器官的混沌控制控制衰老现象的研究”。我们的研究结果表明,使用人工器官控制衰老是可行的。少
英文摘要
Since an aging society comes unescapable, we cope with various diseases by the Aging, and have the necessity of aiming at the society where healthy elderly people play an active part. Although an Aging phenomenon can also be considered to be change of the whole body, in the medical spot, it servers as generating of the illness of an internal-organs unit. The illnesses of an internal-organs unit are various medicines and adaptation of a surgical operation. To the internal-organs malfunction which has advanced irreversibl, radical correspondence of transplantation, an artificial organ, etc. becomes indispensable to life maintenance. Therefore, a possibility that support of high-tech medical treatments, such as an articial organ, will become unescapable at the healthy aging society is high. It is becoming old memory with collapse of the Communist bloc that the long-term struggle for existence of the animal experiment of an artificial heart was performed having applied national prestige al … More l over the world. There is an opinion about which it whispered between the artificial heart researchers in the world from that time. It is "aging of the animal after implanting an artificial heart is early ?" It is the hypothesis to say. To pathophysiological change which can be regarded also as promotion of such an Aging after implanting an artificial heart, the syndrome of a "artificial heart syndrome" was proposed in the University of Tokyo. Research on change of the heart blood vessel system in connection with various artificial circulation and Agings has been done even in Tohoku University. The Institute of Development, Aging and Cancer in Tohoku University carried out the research subject "the nonlinear analysis of the artificial heart animal as an Aging promotion model" by the support of the test research from the Ministry of Education science research cost. Cousequently, the artificial heart chronic animal as an Aging promotion model was established. Based on this result, the Ministry of Education, Culture, Sports, Science and Technology science research cost base research "research on control of the Aging phenomenon by chaos control of an artificial organ" was done from 1999 to 2003. Our results suggested the feasibility of control of Aging by the use of the artificial organs. Less
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T.Yambe: "Searching for the origin of chaos"IEEE EMBS book. 32 (2001)
T.Yambe:《寻找混沌的起源》IEEE EMBS 书。
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T.Yambe, M.Yoshizawa, R.Taira, A.Tanaka, K.Tabayashi, S.Tobita, S.Nitta: "Fluctuations of Emax of the left ventricle: effect of atrial natriuretic polypeptide"Biomed Pharmacother. 55. 147-152 (2001)
T.Yambe、M.Yoshizawa、R.Taira、A.Tanaka、K.Tabayashi、S.Tobita、S.Nitta:“左心室 Emax 的波动:心房利尿钠多肽的作用”Biomed Pharmacother。
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T.Yambe, et al.: "Evaluation of the cardiac function by chaos theory"Artif Organs. (in press). (2001)
T.Yambe 等人:“通过混沌理论评估心脏功能”Artif Organs。
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T.Yambe, et al.: "Totally implantable ventricular assist system which can increase the brain blood flow."Artif Organs. 23. 644-647 (2000)
T.Yambe 等人:“完全植入式心室辅助系统,可以增加脑血流量。”Artif Organs。
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T.Yambe, et al.: "Nonlinear dynamical analysis of the hemodynamic behaviors during the virtual reality immersion"Biomed Pharmacother. 56. 367-369 (2002)
T.Yambe 等人:“虚拟现实沉浸期间血流动力学行为的非线性动力学分析”Biomed Pharmacother。
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共 39 条
Nonlinear analysis of the hemodynamics in the artificial heart animals as the aging acceleration model
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批准号:06558118
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$3.84万
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财政年份:1994
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负责人:YAMBE Tomoyuki
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依托单位:
海外基金