Experimental Study of Osteoconductivity in the cranial bone defect
Experimental Study of Osteoconductivity in the cranial bone defect
批准号:
15591902
负责人:
NINOMIYA Kunitosi
金额:
$2.11万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2003
资助国家:
日本
项目状态:
已结题
起止时间:
2003 至 2006
中文摘要
研究了β-磷酸三钙(β-TCP)对兔颅骨缺损的骨传导作用。在颅骨区域,新生儿对骨骼的吸收是通过薄膜制骨完成的。利用临床应用于人体四肢的人工骨,可以应用于颅骨区域或研究。此外,我们还使用了一根人造骨,并恢复了颅骨的传导活动。一般来说,据说骨膜、硬脑膜、脑膜的每一个缝合部位都会参与其中。利用β-TCP观察颅骨内可见部位骨的传导活性。在修复后的6周内,新生骨暂时大量形成,从12周开始,材料面积的速率下降。材料的面积率,以及新生骨头的面积率,在它修复后,每一群人都是不均匀的,这两种恒定的趋势在六个星期内都没有看到。在实际实验中,在骨膜侧和硬脑膜侧可见压迫骨形成的倾向。此外,从它接受骨周围和硬脑膜的方向来看,它的趋势被认为是新生骨的方向。
英文摘要
We investigated the osteoconductivity of β-Tricalcium Phosphate (β-TCP) on the rabbits' cranial bone defect. In the skull area, newborn absorption of the bone is done by a film bone making. It was possible to apply in the skull area or it researched by using the artificial bone applied clinical by human limbs Choucdahone. Moreover, an artificial bone was used and conduction activity of the skull was retrieved. In general, it is said that each suture part of the periosteum, the dura mater, and the brainpan will take part in it. Conduction activity of the bone was observed from which part to be seen in the skull by using the β-TCP. Temporarily a large amount of, newborn bone is formed as for the result on six weeks after it makes amends, and the rate of the area of the material decreases from 12 weeks. The rate of the area of the material, and as for the rate of the area of a newborn bone, after it made amends, each crowd was also uneven and both constant tendencies were not seen for six weeks. The tendency to press the bone formation in the actual experiment was seen on the periosteum side and the dura mater side. Moreover, the tendency seen from respect where it had received the bone surroundings and the dura mater was suggested as for the direction of a newborn bone.
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