Joint Theoretical and Experimental Electron Momentum Spectroscopic Studies for DNA Bases

DNA结构的研究是一个激烈的研究活动领域，并继续揭示新的水平的复杂性和多样性。最近的实验（Science, 2002）提供了腺嘌呤非平面性的直接证据，表明DNA碱基的非刚性。电子动量谱（EMS）已被认为是在分子水平上研究化学结合机理和轨道的一种合适技术。该项目的目的是利用动量空间量子力学和EMS实验技术研究DNA和RNA碱基如腺嘌呤、胸腺嘧啶（尿嘧啶）、鸟嘌呤和胞嘧啶的轨道和相互作用。该项目的成果将提高我们对DNA双螺旋链结构的认识。

The study of DNA structure is an area of intense research activity and continues to reveal new levels of complexity and diversity. Recent experiments (Science, 2002) provided direct evidences of the adenine non-planarity, indicating non-rigidity of DNA bases. Electron momentum spectroscopy (EMS) has been identified to be an appropriate technique in the study of chemical binding mechanism and orbitals at molecular level. The aims of the project is to study orbitals and interactions of DNA and RNA bases such as adenine, thymine (uracil), guanine and cytosine using momentum space quantum mechanics and EMS experimental techniques. The outcome of the project will improve our understanding of the DNA double helical strand structure.