Cross sectional survey on risk factors for ischemic heart diseases in Japanese middle-aged female

为了评估C反应蛋白(CRP)水平、微量白蛋白尿、B型钠肽(BNP)与心血管疾病(CVD)的其他危险因素之间的关系，岩手健二研究(Iwate-Kenpoku队列研究)始于2002年。所有研究对象都来自岩手县尼诺河、MJYAKO和Kuji地区。2002年至2003年，12,144名受试者参加了血压、总胆固醇、低密度脂蛋白和高密度脂蛋白水平、体重指数(BMJ)、病史、吸烟和饮酒习惯、C反应蛋白(CRP)水平、尿白蛋白排泄(UAE)和BNP水平的检测。本研究以5514名40~69岁(58.0±7.9)岁的女性为研究对象，对其与心血管疾病危险因素之间的关系进行了研究，发现UAE水平与血压、UAE与BMJ、UAE与CRP、CRP与血压、CRP与BMJ、CRP与HbAlc、CRP与血脂之间存在显著的相关性。BNP水平与UAE、BNP、CRP水平无明显相关性。

To evaluate the relationship among C-reactive protein (CRP) levels, microalbuminuria, B-type Na+ Peptide (BNP) and other risk factors of cardio vascular disease (CVD), Iwate-KENCO study ( Iwate-KENpoku COhort study ) started in 2002. All subjects studied were recruited from NINOHE, MJYAKO and KUJI areas in Iwate prefecture. In 2002 -2003, 12, 144 participants were enrolled and blood pressure, total, LDL and HDL cholesterol levels, body mass index (BMJ), medical history, smoking arid drinking habits, CRP levels, urinary albumin excretion (UAE) levels and BNP levels were examined. In this study, 5,514 female aged 40-69 ( 58.0 +-7.9 ) were selected and the relationship among risk factors of CVD was investigated.The significant relationship between UAE levels and blood pressure, UAE and BMJ, UAE and CRP levels, CRP and blood pressure, CRP and BMJ, CRP and HbAlc, CRP and lipid were observed. The relationship between BNP levels and UAE, BNP and CRP levels were not significant.