Antioxidant Agents Therapy for Esophageal Mucosa with Inducible Nitric Oxide Syntlaase Expression

2002年：将蓝莓（花色苷）10%、芝麻（芝麻素）10%、姜黄（姜黄素）10%混合制成抗氧化饲料。治疗组大鼠给予N-甲基-N-氨基葡萄糖胺（AMN后），自给予抗氧化饲料一周。给予抗氧化饲料和AMN的人群和给予正常饲料和ANN的对照人群，每8周给予12周，持续10周，并处死。8周时iNOS的出现已被接受，但致癌频率被抑制。10周后，所有大鼠均在12周内接受致癌。由于抗氧化饲料的摄入情况，一些含有姜黄的饲料咬它并大量保留在计量器的底部，并且认为姜黄的效果不多，但是当继续一起施用致癌剂时，这些抗氧化剂的质量的致癌预防效果可能会降低。 ...更多信息 y致癌作用，但没有提供完全控制致癌作用的假设。2003年：我们再次分析了2002年的一项研究结果。如果我们在8周内完全致癌，然后按常规AMN的剂量饲养8周，直到12周，100%致癌是所提供的情况，与对照大鼠相比，AMN的致癌时间与最初认为的时间有很大的不同。因为我们通常使用的AMN从其他化学试剂公司购买AMN，因为发布被取消，所以认为致癌时间因AMN纯度的差异而改变。AMN大鼠致癌实验是本单位自行开发的致癌实验系统，除常规积累的AMN剂量密度和给药周期数据外，未见文献补充足够的检验。现进行AMN给药期6周、5周、4周、2周之间的致癌基础实验。1再次设定致癌给药期与AM给药特定饲料剂量大鼠之间的结果。少

2002 : We made the antioxidation feed which mixed blueberry (anthocyanins)10% sesame (sesamin) 10%, turmeric (curumin)10% with each. It was given the group of treatments rat N-Methyl-N-anyhtitrosamine (following AMN) since administered antioxidation feed for one week. The crowd whom administered antioxidation feed and AMN to and the control crowd whom administered normal feed and ANN to administered it with 12 weeks for ten weeks for each eight weeks, and sacrifice was made to die. The appearance of iNOS was accepted in eight weeks, but cancer-Causing frequency was held down. For ten weeks, carcinogenesis was accepted in 12 weeks by all rats. As the intake situation of antioxidation feed, some feed with turmeric bit it and remained in a bottom of a gauge in large quantities, and it was thought that there were not most of the effects of turmeric, but when continued administering a cancer-causing agent together, a carcinogenesis prevention effect by quality of these antioxides might dela … More y carcinogenesis temporarily, but that the effect that completely controlled carcinogenesis was not provided was supposed.2003 : We analyzed a study result of 2002 again. If we did carcinogenesis entirely in eight weeks and bred it by the dosage for eight weeks in conventional AMN afterwards until 12 weeks, careinogenesis of 100% was the provided situation and, with a rat of control, was different from the time that the cancer-causing time by AMN thought about at first greatly. Because AMN which we used conventionally purchased AMN from an other chemical reagent company because release was called off, it is thought that the cancer-causing time changed by a difference of purity of AMN. A rat carcinogenesis experiment by AMN was cancer-causing experiment system developed in this institution and there was not a document and added enough examination besides conventional accumulation data about the dosage density and a dosage period of AMN. Now do cancer-causing fundamental experiment between the dosage period of AMN for six weeks for five weeks for four weeks for two weeks.1 set the result between the dosage period for the cause again and am to administer AMN to a special feed dosage rat. Less