Innovative Synthetic Reactions

本研究课题的目标是发现导致新反应的新现象，为新世纪合成化学的发展奠定基础。人们一直致力于寻找新的有效方法来裂解碳与其他元素（包括碳、氮、氧和氢）之间的惰性键，为此，主要基于有机金属反应的各种方法已经被采用。采用了基于理性设计的方法以及探索性方法。反应物-试剂在多个反应中心同时发生相互作用的反应一直是人们广泛关注的问题。结果，成功地开发了各种创新的合成反应。在三年的研究期间，通过几次研讨会，八十个研究小组成功地进行了合作。

The objective of this research project is to discover new phenomena leading to new reactions which will serve as basis for the development of synthetic chemistry in the new century. The efforts have been expected to be devoted to find new efficient method for the cleavage of unreactive bonds between carbon and other elements including carbon, nitrogen, oxygen, and hydrogen.For this purpose various approaches, mainly on the basis of organometallic reactions, have been undertaken. Rational design-based approach as well as exploratory approach was applied. The reactions in which simultaneous reactants-reagents interaction at many reaction centers have been extensively looked for. As the results, various innovative synthetic reactions have been developed successfully. The examples are the catalytic addition of otherwise unreactive C-H bonds to multiple bonds and catalytic, highly stereoselective polymerization.Cooperation among eighty research groups has been successfully done through several symposiums during the three years research period.