Probing confinement enhanced precatalyst association in Pd catalyzed enyne cycloisomerizations by advanced NMR spectroscopy (B08*)

催化烯炔环异构化反应的钯氢化物通常是由弱的Brunsted酸与Pd(0)络合物反应形成的，通常只在很小的平衡浓度下存在。然而，由于较高的局部浓度和与孔壁的相互作用，通过限制可以大大提高活性催化剂的比例和催化选择性。在本项目中，我们将使用先进的MAS核磁共振技术(如HETCOR和REDOR)来观察限制对孔内氢化钯生成平衡的影响，并解释其对烯炔环异构化催化活性和选择性的影响。

Palladium hydrides that catalyze enyne cycloisomerization reactions, typically formed in situ by reaction of weak Brönsted acids with Pd(0) complexes, are often only present in small equilibrium concentrations. The proportion of active catalyst as well as the catalytic selectivity can be, however, vastly increased through confinement due to the higher local concentration and interaction with the pore walls. In this project, we will use advanced MAS NMR techniques (such as HETCOR and REDOR) to observe the effect of confinement on the equilibrium of palladium hydride formation in pores and explain the effect on the catalytic activity and selectivity for enyne cycloisomerization.