Quantitative Evaluation of Hydrophilic-Hydrophobic Interaction in Amphiphilic Polymers

详细研究了含硅或氟原子的新型两亲性聚合物的自组装行为。用小角X射线和中子散射技术分析了溶液中的聚合物聚集体，用X射线反射率测量研究了气-水界面的聚合物单分子膜。一种具有亲水性聚氧乙烯侧链的梳状两亲性聚硅环丁烷(SB)，作为单分子溶解在甲醇或水中。反之，疏水性SB与亲水性甲基丙烯酸2-羟乙酯(HEMA)形成1：1嵌段共聚物，或疏水性聚苯乙烯与亲水性聚(3-羟甲基硅环丁烷)在甲醇中形成以疏水为核的胶束。同样，它们在甲苯中形成了具有亲水核的反胶束。由SB和HEMA组成的1：1嵌段共聚物在水面形成了均匀稳定的单分子膜。水溶性乙烯基醚嵌段共聚物由一个短的不溶于水的氟化链段和一个长的水溶性极性链段组成，在水中形成核壳胶束，与非氟化嵌段共聚物一样。值得注意的是，含氟嵌段共聚物形成的胶束可以选择性地增溶含氟化合物和非含氟水不溶化合物的混合物。这些结果为评价两亲聚合物的亲水-疏水相互作用提供了有用和重要的信息。

Self-assembly of novel amphiphilic polymers containing silicon or fluorine atoms were investigated in detail. Small angle X-ray and neutron scattering techniques were employed for the analysis of the polymer aggregates in solution and X-ray reflectivity measurements were applied to the study of the polymer monolayers at the air-water interface. A comb-like amphiphilic polysilacyclobutane (SB) with hydrophilic polyoxyethylene side chains dissolved as a single molecule in methanol or water. contrast, a 1 : 1 block copolymer composed of hydrophobic SB and hydrophilic 2-hydroxyethyl methacrylate (HEMA) or a 1 : 1 block copolymer composed of hydrophobic polystyrene and hydrophilic poly (3-hydroxymethylsilacyclobutane) formed micelles with hydrophobic core in methanol. Similarly they formed reversed-micelles with hydrophilic core in toluene. A 1 : 1 block copolymer composed of SB and HEMA formed uniform and stable monolayer at the water surface. A water-soluble vinyl ether block copolymer consisting of a short water-insoluble fluorinated segment and a long water-soluble polar segment formed core-shelled micelles in water as in the same way of non-fluorinated block copolymers. It is worth noting that the micelles formed by the fluorine-containing block copolymer could selectively solubilize fluorinated compounds from the mixture of fluorinated and non-fluorinated water-insoluble compounds. These results provided useful and important information for the evaluation of the hydrophilic-hydrophobic interaction of amphiphilic polymers.